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Traditional Chinese medicine formulation for treating and preventing diabetes and its angiopathy

A traditional Chinese medicine preparation and vascular disease technology, which is applied in the field of traditional Chinese medicine preparations for the treatment and prevention of diabetes and vascular disease, can solve the problems of inability to meet clinical drug requirements and lack of drugs, and achieve the effects of delaying cataracts, lowering blood pressure and lowering blood sugar.

Active Publication Date: 2006-04-05
SHANGHAI FANGXIN HEALTH TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the clinical and research in this area is still in the early stage in China, and there are very few effective drugs on the market, which cannot meet the needs of clinical medication. In view of this point, a Chinese medicine preparation for the treatment and prevention of diabetes and its vascular lesions is developed to provide The demand for medicines in the market is of great significance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] Embodiment 1 The preparation method of capsule of the present invention

[0109] Weigh 560 grams of habitat, 316 grams of dogwood, 380 grams of astragalus, 333 grams of baicalin, 312 grams of Sophora japonica, 252 grams of silkworm, 500 grams of motherwort, 226 grams of ghost arrow feather, and 166 grams of emblica. The total amount of crude drug is about 3000g, add water to decoct twice, add 8 times the amount of water to decoct for 2 hours for the first time, add 6 times the amount of water for the second time to decoct for 1 hour, combine the decoction, filter, and let the filtrate stand for 18 hours, take Concentrate the supernatant to a clear paste with a relative density of 1.35 (90°C), add 20% by weight starch, stir well, dry under reduced pressure at 60°C for 24 hours, pulverize, pass through a 40-mesh sieve, and dry at 60°C-80°C until the water content is low Add an appropriate amount of magnesium stearate at 3%, pack into capsules, and make 1000 capsules, 0.3g...

Embodiment 2

[0110] Embodiment 2 The preparation method of capsule of the present invention

[0111] Weigh 562 grams of Cornus officinalis, 150 grams of raw land, 750 grams of astragalus, 115 grams of scutellaria baicalensis, 188 grams of Sophora japonica, 375 grams of silkworm, 712 grams of motherwort, 75 grams of ghost arrow feather, and 80 grams of emblica. The total amount of crude drug is about 3000g, add water to decoct twice, add 8 times the amount of water to decoct for 2 hours for the first time, add 6 times the amount of water to decoct for 1 hour for the second time, filter, combine the filtrates, settle for 18 hours, and take the supernatant Concentrate to a clear paste with a relative density of 1.35 (90°C), add 20% by weight of starch, stir well, dry under reduced pressure at 60°C for 24 hours, pulverize, pass through a 40-mesh sieve, and dry at 60°C-80°C until the water content is less than 3% , add an appropriate amount of magnesium stearate, pack into capsules, and make 10...

Embodiment 3

[0112] Embodiment 3 treatment case

[0113] A 62-year-old male patient had intermittent edema for 5 years, general fatigue for 1 month, abdominal distension, nausea and vomiting, decreased urine output (about 500-800ml per day), and increased urine foam. He had hypertension for 20 years and his blood pressure was as high as 230 / 100mmHg, diabetes history for 10 years, examination: urine protein++, 24-hour urine protein quantification 15.18g / 24 hours, blood urea nitrogen 11.9mmoL / L, creatinine 342umoL / L, fasting blood sugar 11.6mmol / L, 2 hours after meal Blood sugar 18.9mmol / L. Orally take this traditional Chinese medicine capsule preparation three times a day, 4 capsules each time. After 3 months of treatment, the blood pressure of the patient tends to be normal, the symptoms of general edema and general fatigue disappear, and the spirit, appetite, and sleep are all OK. The test results show: Urinary protein ±, creatinine 135.5μmol / L, blood urea nitrogen 7.2mmol / L, fasting blo...

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Abstract

Disclosed is a Chinese medicinal preparation for the treatment and prevention of diabetes and angiopathy, wherein the active compositions include nine kinds of medicinal ingredients (by weight portions) including, cornus officinalis 2-15 parts, dried rehmannia root 1-12 parts, astragalus root 5-30 parts, motherwort 4-20 parts, winged euony twigs 2-10 parts, baikal skullcap root 3-15 parts, sophora flower 2-8 parts, batryticated silkworm 2-10 parts, emblic leafflower fruit 1-4 parts. The new dosage types of the medicinal preparation include capsule.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating and preventing diabetes and its vascular lesions. Background technique: [0002] The prevalence of diabetes is increasing year by year in the world. According to the World Health Organization (WHO) estimate in 1995, the total number of diabetic patients in the world has exceeded 120 million. By 2050, the number of diabetic patients in the world will reach 300 million. The adult prevalence rate in my country is about 2.5%, which is more than three times higher than the prevalence rate 15 years ago. It is estimated that there are more than 20 million diabetic patients in the country. Diabetes is prone to a variety of complications, especially the chronic complications of diabetes with microvascular and macrovascular lesions as the main pathological basis, which can affect almost all organs and tissues and become t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61P3/10A61K35/64
Inventor 张昕
Owner SHANGHAI FANGXIN HEALTH TECH DEV
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