Detection system for up-converting phosphor immune chromatography test paper

An immunochromatography test strip and detection system technology, which is applied in the field of up-conversion phosphorescence immunochromatography test strip detection system, can solve the problems affecting the detection results, laser jitter, operating speed limit, etc., and achieve the elimination of drive circuits and stability Effect with low requirements and strong control ability

Inactive Publication Date: 2006-05-03
SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI +2
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  • Claims
  • Application Information

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Problems solved by technology

[0007] 2. High requirements on the stability of the excitation light source
Since the signal acquisition is completed through long-term mechanical scanning, the acquisition of the signal on the test strip cannot be completed synchronously, so the instability of the output performance of the excitation light source will affect the detection results
[0008] 3. Signal reliability is affected
During the scanning process, the laser may vibrate due to mechanical movement, resulting in fluctuations in illumination intensity and affecting acquisition
[0009] 4. Complicated operation
In the process of data processing, manual intervention is required, which affects the speed and increases the complexity of the operation
[0010] 5. Waste of resources
Control and data processing through PC computer actually only utilizes a small part of the many functions of PC computer, while other functions cannot be used but still occupy processing time and resources, resulting in waste of time and power consumption
The operating speed is greatly limited, and due to the large power consumption, dry batteries cannot be used for power supply, so that the instrument cannot work independently

Method used

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  • Detection system for up-converting phosphor immune chromatography test paper
  • Detection system for up-converting phosphor immune chromatography test paper
  • Detection system for up-converting phosphor immune chromatography test paper

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Embodiment Construction

[0040] The present invention will be further described below in conjunction with the accompanying drawings and embodiments, but the protection scope of the present invention should not be limited thereby.

[0041] see figure 1 , figure 1 It is a structural block diagram and an optical path diagram of an embodiment of the present invention. It can be seen from the figure that the up-conversion phosphorescence immunochromatography test strip detection system of the present invention is composed of an illumination system, an imaging system, a one-dimensional CCD11, a data acquisition circuit 8, and a control system 9. :

[0042] Described illumination system comprises a semiconductor laser 1, on the output optical path of this semiconductor laser 1 is successively fiber bundle 2, collimating lens 3, dichroic mirror 4, front lens group 5, until test paper 10, this test paper The strip 10 is located on the object surface of the front mirror group 5, and the angle between the refl...

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Abstract

The invention relates to an upper rectification phosphorescence immune chromatographic test paper testing system which comprises: the lighting system comprises an exciting light source and an optical fiber beam, a collimation lens, a dichroic mirror and a front mirror group on the output light path of the exciting light source, wherein the test paper is on the object plane of the front mirror group; the angle between the reflecting side of the dichroic mirror and the light shaft is 45 deg.; the imaging system is formed by a front mirror group with the same light shaft, a dichroic mirror, a light filter and a rear mirror group; the phosphorescence image receiver is CCD which is on the image plane of the rear mirror group; the output end of CCD is connected with the data collecting circuit which is connected with a control system.

Description

technical field [0001] The present invention relates to up-conversion phosphorescence labeling technology, in particular to an up-conversion phosphorescence immunochromatography test strip detection system. Qualitative and quantitative detection of various target objects such as illegal drugs. Background technique [0002] Up-conversion phosphorescence technology is a new type of labeling technology developed based on up-conversion phosphorescent materials. The conversion of long-wavelength radiation into short-wavelength radiation by special mechanisms is called upconversion. A special material having an up-converting phosphorescence phenomenon is called an up-converting phosphorescent material (Up-Converting Phosphor hereinafter referred to as UCP). When excited with infrared light, the material emits visible light at a wavelength much shorter than the excitation light. If the up-converting luminescent particles and bioactive molecules are connected by covalent bonds to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64G01N33/52G01N33/558
Inventor 刘蕾周蕾王静黄立华闫中强胡孔新赵永凯杨瑞馥李伟黄惠杰曾爱军余琨王大宁王宝麟
Owner SHANGHAI INST OF OPTICS & FINE MECHANICS CHINESE ACAD OF SCI
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