Medicinal composition containing safflower total flavone and its preparation process and usage
The technology of total flavonoids and composition of safflower is applied in the field of medicine, which can solve the problems of insufficient treatment effect of cardiovascular and cerebrovascular diseases, lack of clinical use, complicated and time-consuming processing, etc., so as to maintain nerve stress ability, improve microcirculation, and achieve finished products. rate increase effect
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Embodiment 1
[0024] The preparation of embodiment 1-pharmaceutical composition
[0025] Add 30 times the volume of 15% ethanol solvent to the original medicinal material of safflower, use a microwave with a frequency of 1100 MHz and a power of 12000 watts, extract 5 times under the condition of 70 ° C, 50 minutes each time, combine the extracts, and use NaOH or Adjust the pH to 7-8 with hydrochloric acid, add a chitosan solution with a concentration of 0.5%, stir, let stand for 1-2 hours, filter, and dry the filtrate under reduced pressure at 65°C to an extract with a specific gravity of 1.25-1.30, namely For the total flavonoids of safflower. The total flavonoids are stored under refrigeration, and the temperature of refrigeration is controlled between 0 and 4°C. Proportioning is carried out according to the weight of acetylglutamine being 15 times of total flavonoids of safflower.
Embodiment 2
[0026] The preparation of embodiment 2-pharmaceutical composition
[0027]Add 50 times the volume of 30% ethanol solvent to the original medicinal material of safflower, use a microwave with a frequency of 1100 MHz and a power of 12000 watts, extract 5 times under the condition of 70 ° C, 50 minutes each time, combine the extracts, and use NaOH or Adjust the pH to 7-8 with hydrochloric acid, add a chitosan solution with a concentration of 0.5%, stir, let stand for 1-2 hours, filter, and dry the filtrate under reduced pressure at 65°C to an extract with a specific gravity of 1.20-1.50, namely For the total flavonoids of safflower. The total flavonoids are stored under refrigeration, and the temperature of refrigeration is controlled between 0 and 4°C. According to the weight of acetylglutamine being 18 times of the total flavonoids of safflower, it is prepared.
Embodiment 3
[0028] The preparation of embodiment 3-pharmaceutical composition
[0029] Add 200 times the volume of 45% ethanol solvent to the original medicinal material of safflower, use a microwave with a frequency of 1100 MHz and a power of 12000 watts, extract 5 times under the condition of 70 ° C, 50 minutes each time, combine the extracts, and use NaOH or Adjust the pH to 7-8 with hydrochloric acid, add a chitosan solution with a concentration of 0.5%, stir, let stand for 1-2 hours, filter, and dry the filtrate under reduced pressure at 65°C to an extract with a specific gravity of 1.25-1.30, namely For the total flavonoids of safflower. The total flavonoids are stored under refrigeration, and the temperature of refrigeration is controlled between 0 and 4°C. According to the weight of acetylglutamine being 18 times of the total flavonoids of safflower, it is prepared.
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