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Chinese medicine formulation of lunar caustic for activating blood flow and removing blood stasis, and stopping pain, and its preparing method

A traditional Chinese medicine preparation, promoting blood circulation and removing blood stasis technology, applied in medical formula, medical preparations containing active ingredients, drug delivery, etc., to achieve the effects of less irritation, increased stability, and high bioavailability

Active Publication Date: 2006-08-09
贵州君之堂制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to: provide a kind of traditional Chinese medicine preparation and its preparation method for blood circulation promoting and blood stasis dispelling, dredging meridians and relieving pain; The present invention provides pellets and dispersible tablets with good disintegration and high bioavailability according to the prior art , especially suitable for infants, the elderly, and patients who have difficulty swallowing tablets or capsules; the soft capsule preparation provided by the invention is made by sealing the drug in a soft rubber shell, which solves the problem of drug instability when encountering damp heat, and can also Cover up the bad taste and smell of the drug, increase the stability and improve the bioavailability; the granules provided by the invention have a good taste, do not need to disintegrate, are fast absorbed, and are convenient to take

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0179] Embodiment 1 of the present invention: Preparation 1 of granules

[0180] Take 17g of ginkgo leaves, add 70% ethanol to extract twice, each time for 2 hours, filter, recover ethanol from the filtrate, and dry the concentrated solution to get powder; take 22g of salvia miltiorrhiza, add water to decoct 3 times, the first time for 3 hours, the second time 2 hours, 1 hour for the third time, filter, combine the filtrates for 3 times, concentrate to 20°C and measure the relative density to 1.20, add ethanol and stir to precipitate, take the supernatant to recover ethanol, dry the concentrated solution to obtain powder; take 13g of Gynostemma pentaphyllum , add 75% ethanol to extract 2 times, each time for 2 hours, filter, reclaim ethanol from the filtrate, and dry the concentrated solution to obtain a powder; grind 2.5g of moxa tablets into fine powder, mix with the powder prepared in the above three items; Add 1.5% aspartame and 5% starch, mix evenly, granulate, dry, granu...

Embodiment 2

[0181] Embodiment 2 of the present invention: preparation 2 of granules

[0182]Take 17g of Ginkgo biloba leaves, add 70% ethanol to extract twice, each time for 2 hours, filter, recover ethanol from the filtrate, and dry the concentrated solution to get powder; take 45g of Salvia miltiorrhiza, add water to decoct 3 times, the first time for 3 hours, the second time 2 hours, 1 hour for the third time, filter, combine the filtrates for 3 times, concentrate to 20°C, measure the relative density to 1.20, add ethanol and stir to precipitate, take the supernatant to recover ethanol, dry the concentrated solution to obtain powder; take 25g of Gynostemma pentaphyllum , add 75% ethanol to extract 2 times, each 2 hours, filter, the filtrate reclaims ethanol, and the concentrated solution is dried to obtain powder; 5g of moxa tablets are pulverized into fine powder, and mixed with the powder prepared by the above three items; by weight Add 2.5% aspartame and 15% starch, mix evenly, gran...

Embodiment 3

[0183] Embodiment 3 of the present invention: preparation 3 of granules

[0184] Take 17g of ginkgo leaves, add 70% ethanol to extract twice, each time for 2 hours, filter, recover ethanol from the filtrate, and dry the concentrated solution to get powder; take 67g of salvia miltiorrhiza, add water to decoct 3 times, the first time for 3 hours, the second time 2 hours, 1 hour for the third time, filter, combine the filtrates for 3 times, concentrate to 20°C and measure the relative density to 1.20, add ethanol and stir to precipitate, take the supernatant to recover ethanol, dry the concentrated solution to obtain powder; take gynostemma 37g , add 75% ethanol to extract 2 times, each time for 2 hours, filter, reclaim ethanol from the filtrate, and dry the concentrated solution to obtain a powder; 7.5g of moxa tablets are crushed into fine powder, and mixed with the powder obtained from the above three items; Add 4% aspartame and 30% starch, mix evenly, granulate, dry, granulat...

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Abstract

The present invention provides a Yindan Chinese medicine preparation with the functions of promoting blood circulation, removing blood stasis, promoting circulation of qi and stopping pain with good therapeutic effect and its preparation method. Said Yindan Chinese medicine preparation is made up by using (by weight portion) 17-52 portions of ginkgo leaf, 22-67 portions of salvia root, 13-37 portions of gynostemma pentaphyllum, 2.5-7.5 portions of mugwort leaf and proper quantity of auxiliary material through a certain preparation process. Said preparation can be made into various dosage forms.

Description

Technical field: [0001] The invention relates to a Yindan traditional Chinese medicine preparation for promoting blood circulation, removing blood stasis, dredging channels and relieving pain and a preparation method thereof, belonging to the technical field of traditional Chinese medicine pharmacy. technical background: [0002] Middle-aged and elderly people often experience symptoms such as chest obstruction, chest tightness, chest pain, palpitations, and shortness of breath, which are caused by congestion and obstruction, and these symptoms have seriously affected people's health. But there are no good drugs to treat this disease. Therefore, it is very important to invent a kind of drug with definite curative effect, safe and convenient, little side effect for promoting blood circulation and removing blood stasis, dredging channels and relieving pain. In order to achieve the purpose of prevention and treatment, many inventors and pharmaceutical companies have done a lar...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K9/00A61P9/10A61P9/00
Inventor 张沛
Owner 贵州君之堂制药有限公司
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