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Compound preparation for prevention and treatment adiposis and its prepn. method

A compound preparation and obesity technology, applied in medical preparations containing active ingredients, pharmaceutical formulas, active ingredients of sulfur/selenium/tellurium, etc., can solve problems such as gastric irritation, achieve weight loss immunity, and improve antioxidant capacity and stability, the effect of improving immunity

Inactive Publication Date: 2006-09-20
INST OF GEOGRAPHICAL SCI & NATURAL RESOURCE RES CAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the number and variety of such products are increasing, but most of the above products are acid-type preparations of CLA, which have a certain stimulating effect on the stomach of users

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Weigh 93g of conjugated linoleic acid in 930ml of distilled water, add 135ml of 10%wt sodium hydroxide solution to react, and form a transparent solution, then add 474ml of 10%wt magnesium chloride hexahydrate solution, stir to form white granular conjugated linoleic acid Magnesium linoleate is filtered, washed with distilled water, dried, and pulverized to obtain about 97 grams of intermediate product conjugated magnesium linoleate of the present invention.

[0035] Weigh 0.01g of sodium selenite, 3g of vitamin C, and 10g of magnesium conjugated linoleate, mix them evenly, then add the remaining magnesium conjugated linoleate several times, and mix step by step until the total amount; then add A small amount of starch is used as an excipient, mixed evenly, and pressed into tablets.

Embodiment 2

[0037] Weigh 95g of conjugated linoleic acid in 950ml of distilled water, add 138ml of 10%wt sodium hydroxide solution to react, and form a transparent solution, then add 485ml of 10%wt magnesium chloride hexahydrate solution, stir to form white granular conjugated linoleic acid Magnesium linoleate is filtered, washed with distilled water, dried, and pulverized to obtain about 99 grams of the intermediate product of the present invention, conjugated magnesium linoleate.

[0038]Weigh 0.02g sodium selenite, 1g vitamin C, 10g magnesium conjugated linoleate, mix well, then add the remaining magnesium conjugated linoleate in several times, mix step by step until the total amount; then pulverize To 150-200 mesh, made into powder.

Embodiment 3

[0040] Weigh 93g of conjugated linoleic acid in 930ml of distilled water, add 135ml of 10%wt sodium hydroxide solution to react, and form a transparent solution, then add 474ml of 10%wt magnesium chloride hexahydrate solution, stir to form white granular conjugated linoleic acid Magnesium linoleate is filtered, washed with distilled water, dried, and pulverized to obtain about 97 grams of the intermediate product of the present invention, magnesium conjugated linoleate.

[0041] Weigh again 0.00036g sodium selenite, 2g vitamin C (V C ), 10g of magnesium conjugated linoleate, mixed evenly, then the remaining magnesium conjugated linoleate was added in several times, and mixed step by step until the total amount; then a small amount of excipient carboxymethylcellulose was added, Mix well and press into tablets.

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Abstract

A compound medicine in the form dispersing tablet, pill, or coated tablet for preventing and treating obesity is proportionally prepared from conjugated magnesium linoleate, selenite, VC and coating material. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a novel preparation for preventing and treating obesity and a preparation method thereof. Background technique [0002] At present, obesity is spreading all over the world, and the number of patients has reached 300 million. It is the fourth killer after heart disease, cancer and diabetes, which are the biggest threats to human beings today. In Europe, America and some industrial countries, obesity has long been considered the enemy of health. From 1991 to 2001 in the United States, the number of people suffering from obesity rose by 74%, about 44 million, or 20% of American adults, were diagnosed as obese. my country's obesity patients have reached more than 70 million. In recent years, due to the improvement of people's living standards, the incidence of obesity has increased dramatically. [0003] Obesity and overweight lead to diseases such as diabetes, high blood pressure, hyperlipidemia and coronary heart disease, whic...

Claims

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Application Information

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IPC IPC(8): A61K33/04A61P3/04A61K31/375A61K31/201
Inventor 王五一冯福建虞江萍杨林生
Owner INST OF GEOGRAPHICAL SCI & NATURAL RESOURCE RES CAS
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