Cefditoren pivoxil dry suspensoid and its preparing process

A technology of cefditoren pivoxil and dry suspension, which is applied in the directions of pharmaceutical formulas, medical preparations without active ingredients, medical preparations containing active ingredients, etc., and can solve the problem of cefditoren pivoxil dry suspension. Research and reports, single dosage form, unable to meet the needs of medication, etc., to achieve the effect of improving medication compliance, good taste, and facilitating drug absorption

Inactive Publication Date: 2006-10-11
楼剑波 +1
View PDF1 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, only cefditoren pivoxil tablets are sold in China, but the dosage form is single, which cannot meet the medication needs of different types of patients, especially children, the elderly, and patients who have difficulty taking solid preparations such as tablets

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cefditoren pivoxil dry suspensoid and its preparing process
  • Cefditoren pivoxil dry suspensoid and its preparing process
  • Cefditoren pivoxil dry suspensoid and its preparing process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0039] Calculated by preparing 1000 bags, the composition and proportioning of raw and auxiliary materials are:

[0040] Cefditoren pivoxil 100g

[0041] Sucrose 1900g

[0042] Hypromellose 60g

[0043] Protein sugar 20g

[0044] Orange flavor 30g

[0045] Make 1000 bags

[0046] Preparation:

[0047] ①Cefditoren pivoxil passed through a 500-mesh sieve, and the rest of the excipients passed through a 100-mesh sieve.

[0048] ② Weigh 1 / 6 prescription amount of hypromellose and 50% ethanol solution to make a 3% solution for later use.

[0049] ③ Weigh the prescribed amount of cefditoren pivoxil, sucrose, protein sugar and remaining hypromellose, mix evenly, add the above-mentioned adhesive and soft material made of orange essence, granulate with 20 mesh, blow dry at 60°C, and dry for 20 Whole grain.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a Cefditoren pivoxil for suspension and its preparing process, wherein the preparation is prepared from Cefditoren pivoxil, cane sugar, methyl hydroxypropylcellulose, egg white sweets and orange essence through sieving, weighing, mixing homogeneously, charging adhesive, palletizing, forced air drying and granulating.

Description

technical field [0001] The invention relates to a new preparation of cefditoren pivoxil, especially suitable for dry suspension of cefditoren pivoxil for children, the elderly and patients who cannot swallow solid preparations and a preparation method thereof, for treating cefditoren pivoxil infection by susceptible bacteria. Background technique [0002] Cefditoren pivoxil is a fourth-generation cephalosporin drug developed by Meiji Seika Co., Ltd., its chemical structural formula is: [0003] [0004] Molecular formula: C 25 h 28 N 6 o 7 S 3 [0005] Molecular weight: 620.73 [0006] Cefditoren pivoxil English name is cefditoren pivoxil, chemical name: (-)-(6R,7R)-2,2-dimethylpropionyloxymethyl 7-[(Z)-2-(2-amino- 4-thiazolyl)-2-methoxyiminoacetamido]-3-[(Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-5-thia -1-Azabicyclo[4,2,0]octyl-2-carboxylate has a wide range of antibacterial effects on G+ and G- bacteria, especially Staphylococcus, Streptococcus including Strep...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K31/546A61K9/14A61K47/38A61P31/04
Inventor 楼剑波任燕
Owner 楼剑波
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap