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Liquid capsule of heart and brain, and preparation method

A liquid capsule, heart-brain technology, used in capsule delivery, pharmaceutical formulations, cardiovascular system diseases, etc., can solve the problems of incomplete sealing at the shell of hard capsules, unqualified disintegration of soft capsules, and affecting drug quality. , to achieve the effect of improving quality and value, facilitating storage and reducing moisture absorption

Inactive Publication Date: 2006-12-06
江西青春康源制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] 1. Long-term storage of capsules will cause moisture absorption and affect the quality of the drug;
[0004] 2. The seal of the hard capsule shell is not complete, which may easily lead to the degradation of the drug;
[0005] 3. The soft capsule disintegrates during the storage period and is unqualified;
[0006] 4. During the storage period of the soft capsule, the migration of substances in the capsule occurs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The heart and brain liquid capsule of the present invention is made with the following raw materials and methods in weight ratio:

[0026] Rhodiola rosea 666.7g Lycium barbarum 333.3g Seabuckthorn fresh pulp 95.3g Beeswax 3g Edible vegetable oil 0.3Kg

[0027] The method of making the above components into liquid capsules is as follows:

[0028] The above three flavors, Rhodiola plus 60% ethanol reflux extraction twice, the first time is 3 hours, the second time is 2 hours, the extracts are combined, and the ethanol is recovered for later use; wolfberry is decocted twice, each time for 2 hours, combined decoction, filtered, and the filtrate for later use; seabuckthorn fresh pulp was mixed with the above-mentioned ethanol extract and water decoction, concentrated to a clear paste with a relative density of 1.09-1.40, measured at a temperature of 60°C, dried to obtain a dry paste powder, added Appropriate amount of vegetable oil is eaten, stirred and ground for several h...

Embodiment 2

[0030] The heart and brain liquid capsule of the present invention is made with the following raw materials and methods in weight ratio:

[0031] Rhodiola rosea 666.7g Lycium barbarum 333.3g Seabuckthorn fresh pulp 95.3g Beeswax 3g Edible vegetable oil 0.6Kg

[0032] The method of making the above group into liquid capsules is as follows:

[0033] For the above three flavors, Rhodiola plus 20-95% ethanol is reflux extracted twice, the first time is 3 hours, the second time is 2 hours, the extract is combined, and the ethanol is recovered for later use; Lycium barbarum is decocted twice, each time 2 hours , combined the decoction, filtered, and the filtrate was set aside; seabuckthorn fresh pulp was mixed with the above alcohol extract and water decoction, concentrated to a clear paste with a relative density of 1.01-1.20, measured at a temperature of 50°C, and dried to obtain a dry paste powder , add an appropriate amount of edible vegetable oil, stir and grind for several ho...

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PUM

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Abstract

A Chinese medicine 'Xinnao softgel', an improvement to existing Xinnao capsule, is prepared from 5 raw materials: rhodiala root, wolfberry fruit, and fresh juice of hippophae, beeswax and plant oil. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a heart-brain liquid capsule and a preparation method thereof. Background technique [0002] Xinnao Liquid Capsules are refined and developed from traditional Chinese medicine Rhodiola rosea, seabuckthorn fruit and medlar. The compatibility of the three herbs has the functions of promoting blood circulation, replenishing qi and nourishing yin. Among them, Rhodiola rosea is the monarch drug of the group, and it is a traditional precious Tibetan medicine. It is cool in nature, pungent in taste, slightly bitter, and has the functions of breaking firmness, eliminating stagnation, promoting blood circulation, nourishing blood, breaking blood, and improving blood circulation. . Modern pharmacological studies have proved that Rhodiola contains two different superoxide dismutase (SOD) isoenzymes, which have a strong ability to scavenge oxygen free radicals and have a clear and positive anti-altitude hypoxia ef...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61K9/48A61P39/06A61P9/10
Inventor 刘木生马小泉黄样华
Owner 江西青春康源制药有限公司
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