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Preparation process of stomach invigorating and digestion helping tablet

A Jianwei Xiaoshi tablet and its preparation technology are applied in the direction of medical preparations containing active ingredients, digestive system, plant raw materials, etc., which can solve the problems of difficult control of microbial limits, influence on product application and sales, and restrict demand, so as to avoid The problem of exceeding the limit of microorganisms in the finished product, the effect of improving the therapeutic effect of the product, and facilitating transportation and storage

Inactive Publication Date: 2013-04-24
SHANDONG HUAXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is difficult to control the microbial limit of clinical drugs, the content of hesperidin is unstable, the curative effect is not obvious, the taste is poor and other technological problems, which seriously affect the application and sales of this product, restrict the demand of people for medicine, and it is difficult to adapt to modernization , International requirements for solid preparations of traditional Chinese medicine
[0005] At present, the raw powder of Pseudostellaria Pseudostellaria and Chinese yam in Jianwei Xiaoshi Tablets is directly used as medicine, and the active ingredients will be excreted from the body without being effectively released in the stomach. Jianweixiaoshi tablet is a chewable tablet, which contains raw yam powder, which has a poor taste and can also cause throat discomfort and reflex cough
The addition of a large amount of raw powder of medicinal materials resulted in the microbial limit of the preparation exceeding the standard

Method used

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  • Preparation process of stomach invigorating and digestion helping tablet
  • Preparation process of stomach invigorating and digestion helping tablet

Examples

Experimental program
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Effect test

Embodiment 1

[0042] This embodiment is made of the raw materials and auxiliary materials of the following weight ratio: every 1000 tablets are made of the following raw materials and auxiliary materials of the weight ratio: Radix Pseudostellariae 228.6g, dried orange peel 22.9g, Chinese yam 171.4g, malt (stir-fried) 171.4g , Hawthorn 114.3g,

[0043] Sucrose 450g, dextrin 50g, magnesium stearate 3g.

[0044] Its production process is as follows:

[0045] 1) Put tangerine peel in a multifunctional extraction tank, add 8 times the amount of 75% ethanol to extract twice, each time for 1.5 hours, filter, recover ethanol from the filtrate and concentrate to a thick paste with a relative density of 1.08-1.12 (65°C).

[0046] 2) Decoct the whole amount of heterophylla, whole amount of yam, hawthorn, and fried malt with 12 times the amount of water for 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a thick paste, or condense to a relativ...

Embodiment 2

[0054] This embodiment is made of the raw materials and auxiliary materials of the following weight ratio: every 1600 tablets are made of the following raw materials and auxiliary materials of the weight ratio: Radix Pseudostellariae 228.6g, dried orange peel 22.9g, Chinese yam 171.4g, malt (stir-fried) 171.4g , hawthorn 114.3g, sucrose 450g, dextrin 50g, magnesium stearate 3g.

[0055] Its production process is as follows:

[0056] 1) Put tangerine peel in a multifunctional extraction tank, add 8 times the amount of 75% ethanol to extract twice, each time for 1.5 hours, filter, recover ethanol from the filtrate and concentrate to a thick paste with a relative density of 1.08-1.12 (65°C).

[0057] 2) Decoct the whole amount of heterophylla, whole amount of yam, hawthorn, and fried malt with 12 times the amount of water for 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a thick paste, or condense to a relative A clear...

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Abstract

The invention relates to a preparation process of a stomach invigorating and digestion helping tablet. The preparation process comprises the following steps of: extracting tangerine peel by using 75% ethanol, replacing half-quantity extraction of radix pseudostellariae and Chinese yam by combined extraction of full-quantity medicinal materials and other medicinal materials, further pelletizing by taking extractum as an adhesive through a one-step pelletizing technology, mixing and tabletting. According to the preparation process of the stomach invigorating and digestion helping tablet, the stomach invigorating and digestion helping tablet is prepared by carrying out full-quantity medicinal material extraction on the Chinese yam and the radix pseudostellariae and alcohol extraction on the tangerine peel, and the disadvantages of products produced by using the original processes are effectively avoided; effective constituents of the stomach invigorating and digestion helping tablet are easily absorbed and utilized by human bodies; the microbial limit standard exceeding problem of a finished product is effectively avoided, and the mouth feel of the stomach invigorating and digestion helping tablet is improved; by adopting the extraction by using the 75% ethanol, the content of aurantiamarin is nearly doubled or more, so that the content of the aurantiamarin which is a functional constituent in the preparation and the treatment effect of the tablet are substantially improved; all the medicinal materials are prepared into the extractum and pelletized by spraying, the fluidity of prepared particles is good, the appearance of the tablet is neat, the uniformly pressed tablet surface is uniform in color and luster and free of pocking marks and colored patches, and the appearance quality of the tablet is improved; and the quality is stable.

Description

technical field [0001] The invention relates to a preparation process of Jianweixiaoshi tablets, which belongs to the field of pharmaceutical preparations. Background technique [0002] At present, people are more and more concerned about their physical condition, and some minor ailments have gradually come into people's sight. The term "dyspepsia" has gradually entered people's lives. There are endless advertisements on the Internet, especially advertisements targeting children with dyspepsia appear overwhelmingly before people's eyes. Because children's spleen and stomach are not yet fully developed, the incidence of indigestion is higher than that of other groups. The main symptoms are picky eating and anorexia. On the one hand, children are in the growth stage, and parents are worried that indigestion will affect their growth and development, so the need to solve indigestion is more urgent. On the other hand, parents are worried that the side effects of medicines will ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P1/14
Inventor 马媛媛张道远楚大祥梁玉景郭建国张晓燕刘爱华王光西
Owner SHANDONG HUAXIN PHARMA
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