A lock solution for medical devices

A medical device and solution technology, applied in the field of Locke solution, can solve problems such as increased frequency of blood clot deposition and expensive use of antibiotics

Inactive Publication Date: 2007-01-31
GAMBRO LUNDIA AB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the use of taurolidine resulted in an increased frequency of intraductal clot deposition relative to heparin lock solution
Antibiotic use is also very expensive

Method used

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  • A lock solution for medical devices
  • A lock solution for medical devices
  • A lock solution for medical devices

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Experimental program
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Effect test

Embodiment Construction

[0118] Various solutions of the invention are shown in Table 1 below. Solution A is ACD solution for infusion of drugs, solution B is CPDA solution for blood products, solution C is conventional solution for peritoneal dialysis, solution D is conventional solution with lower or high glucose concentration acc.Col III.

[0119] A

B

C

D

3.19% glucose

1.04% citric acid monohydrate

2.87% Sodium Citrate Dehydrate

3.27g / L acidic citric acid monohydrate

26.3g / L sodium citrate

2.51g / L sodium dihydrogen phosphate dihydrate

31.9g / L dextrose monohydrate

275g / L adenine

4.0% glucose

5.4g / L sodium chloride

0.199g / L calcium chloride

0.051g / L magnesium chloride

4.5g / L sodium lactate

Anhydrous hydrochloric acid

pH 5.5

0.1 to 50%

[0120] Various solutions of preferred compositions of carbohydrates, carbonyls and citrates are shown in Table 2:

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Abstract

The present invention relates to a lock solution for medical devices comprising carbohydrate and / or glucose degradation products as antimicrobial agents.

Description

[0001] technical field of invention [0002] The present invention relates to lock solutions for use in medical devices. [0003] Further, the present invention relates to devices for applying the lock solution of the present invention in catheters or other systems for accessing organisms, vasculature, tissue structures or hollow organs. The invention also relates to methods of applying Locke's solution in catheters or other systems for access. Background technique [0004] Intravascular catheters associated with bloodstream infections are a significant cause of disease and excessive medical costs. From a clinical standpoint, health care professionals, ie physicians and nurses, have limited ability to reduce the risk of infection in vascular access, even if they take great care in aseptic technique. Small amounts of bacteria that might not be a problem in the bloodstream can grow in the catheter. have also attributed bacterial resistance to antibiotics to the formation of b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/18A61L33/04A61K31/70A61L29/16A61M
CPCA61L2300/404A61L2300/23A61K31/70A61L29/16A61L2300/42
Inventor A·维斯兰德A·施内尔R·德皮施W·贝克R·迪特里希C·特里克
Owner GAMBRO LUNDIA AB
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