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Insecticide of ivermectin

A technology of ivermectin and pesticides, applied in the field of agricultural pesticides, can solve the problems of endangering human health, high use cost, environmental pollution and the like

Inactive Publication Date: 2010-08-11
SHAANXI SUNGER ROAD BIO SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to develop a new dosage form preparation in order to overcome the existing production and processing dosage forms of ivermectin, the shortcomings of environmental pollution, harm to human health and high use cost that exist in the production and use process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Embodiment 1 0.5% ivermectin microcapsules

[0011] The content of each component (by weight percentage) is ivermectin 0.7%, emulsifier TX-10 4%, 22012%, solvent toluene 4%, DMF 4%, encapsulating monomer polyol modified MDI 2.5%, Antifreeze agent ethylene glycol 4%, thickener xanthan gum 0.3%, wetting and dispersing agent alkylphenol polyoxyethylene ether phosphate 4%, stabilizer sodium benzoate 0.1%, add deionized water to make up 100%.

[0012] After dissolving ivermectin in a solvent, add encapsulating monomer and emulsifier to mix evenly as an oil phase, add it into the water phase under a high-speed shearing machine and shear it, so that the particle size of the emulsion is 1-3 microns, Then, at a suitable temperature and a certain stirring speed, the microcapsules are solidified and enlarged, and the capsule forming reaction is stopped after the system reacts for a certain period of time. Then wetting and dispersing agent, thickener, stabilizer, antifreezing agen...

Embodiment 2

[0013] Embodiment 2 5% ivermectin microcapsules

[0014] The content of each component (by weight percentage) is 5.3% of ivermectin, 3% of emulsifier 2201, 3% of Tween-60, 4% of solvent DMF, 8% of dichloromethane, polyether polyol of encapsulating monomer 5%, antifreeze agent propylene glycol 4%, thickener xanthan gum 0.3%, wetting and dispersing agent phenethylphenol polyoxyethylene ether phosphate 4%, stabilizer sodium sorbate 0.1%, add deionized water to make up 100% %. After dissolving ivermectin in a solvent, add encapsulating monomer and emulsifier to mix evenly as an oil phase, add it into the water phase under a high-speed shearing machine and shear it, so that the particle size of the emulsion is 1-3 microns, Then, at a suitable temperature and a certain stirring speed, the microcapsules are solidified and enlarged, and the capsule forming reaction is stopped after the system reacts for a certain period of time. Then add dispersant, thickener, stabilizer, antifreeze...

Embodiment 3

[0015] Embodiment 3 2.5% ivermectin aqueous emulsion

[0016] Its component content (by weight percentage) is ivermectin 2.8%, emulsifier 2201 3%, 1601 5%, solvent DMF 4%, dichloromethane 6%, antifreeze agent ethylene glycol 4%, add deionized Water makes up 100%. After dissolving ivermectin in a solvent, add an emulsifier and mix evenly as the oil phase, use the mixture of antifreeze and water as the water phase, add the oil phase to the water phase under a high-speed shearing machine and cut for a certain period of time, Make the particle diameter of the emulsion less than 0.8 micron, namely obtain 2.5% ivermectin water emulsion. After inspection, the content is 2.8%, the pH is 6.8, the emulsion stability (diluted 200 times) is qualified, the low temperature stability is qualified, and the thermal storage stability is qualified.

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Abstract

An agricultural insecticide for preventing and eliminating pests and mite of fruit tree and vegetables is prepared from ivermectin (0.5-50%), emulsifier, solvent, bag-forming monomer, wetting disperser, diluent, adhesive and deionized water.

Description

technical field [0001] The invention relates to an insecticide for agricultural crops, in particular to an agricultural insecticide containing ivermectin. Background technique [0002] Ivermectin (English common name: ivermectin, chemical formula C 48 h 74 o 14 , C 47 h 72 o 14 ) is a new type of synthetic pesticide successfully developed with avermectin as the lead compound through double bond hydrogenation and structural optimization. As a structure-optimized product of agricultural antibiotics, compared with the parent abamectin, it not only retains its repellent and acaricidal activities, but also has higher safety and is less likely to produce resistance. It provides a great opportunity for the production of vegetables, fruits and cotton A biological source insecticide with high efficiency, high safety and good environmental compatibility. [0003] At present, ivermectin has only one dosage form of emulsifiable concentrate. Because a large amount of organic solv...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01P7/04A01N25/30A01N43/90
Inventor 郑敬敏王同斌刘健毕标能张崇斌
Owner SHAANXI SUNGER ROAD BIO SCI