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Baicao gel for treating gynecologic inflammation

The technology of Baicao Fu and gel, applied in the field of medicine, can solve the problems of strong foreign body sensation, irritation of vaginal mucosa, short residence time, etc., and achieve the effects of high bioavailability, weak foreign body sensation, and convenient use.

Inactive Publication Date: 2007-06-20
杨伟荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the dosage forms of heat-clearing and detoxifying, insecticidal and antipruritic, and stasis-removing and astringent varieties are relatively single, usually lotions, suppositories, effervescent tablets or foams, etc. The lotion stays in the affected part for a short time, has poor bactericidal effect, and is inconvenient to apply; and Although the suppository stays in the vagina for a long time, it is easy to flow out from the vagina after melting and pollute the clothes. At the same time, because it contains a large amount of glycerin, it is easy to cause bladder edema and a strong foreign body sensation in the vagina; The mucous membrane is irritating to a certain extent; the fluorine-containing propellant in the foam can easily cause the vaginal mucous membrane to fall off

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The preparation method of Baicaofuyanqing gel comprises the following steps:

[0014] Weigh the raw materials of the following weight proportions:

[0015] 640g of Sophora flavescens, 320g of Baibu, 320g of Cnidium, 320g of Agrimony, 320g of Purple Pearl Leaf, 10g of alum, 5g of borneol, 10g of camphor, 60g of boric acid;

[0016] Take the above nine medicinal materials, take Sophora flavescens, Baibu, Cnidium, Agrimony, Agrimony, and add 8 times the amount of water to decoct three times. The first and second times are 2 hours each, and the third time is 1 hour. Filtrate hot, concentrate the filtrate to a clear paste with a relative density of 1.08-1.10 (25°C), add 95% ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter the supernatant, and recover ethanol from the filtrate, Make medicinal material extract for later use, take another 50g carbomer, add appropriate amount of water to swell, grind alum and boric acid into the finest powder, di...

Embodiment 2

[0018] The preparation method of Baicaofuyanqing gel comprises the following steps:

[0019] Weigh the raw materials of the following weight proportions:

[0020] 640g of Sophora flavescens, 320g of Baibu, 320g of Cnidium, 320g of Agrimony, 320g of Purple Pearl Leaf, 10g of alum, 5g of borneol, 10g of camphor, 60g of boric acid;

[0021] Take the above nine medicinal materials, take Sophora flavescens, Baibu, Cnidium, Agrimony, Agrimony, and add 8 times the amount of water to decoct three times. The first and second times are 2 hours each, and the third time is 1 hour. Filtrate hot, concentrate the filtrate to a clear paste with a relative density of 1.08-1.10 (25°C), add 95% ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter the supernatant, and recover ethanol from the filtrate, Prepare the medicinal material extract for later use, take another 67.5g carbomer, add appropriate amount of water to swell, grind alum and boric acid into the finest p...

Embodiment 3

[0023] The preparation method of Baicaofuyanqing gel comprises the following steps:

[0024] Weigh the raw materials of the following weight proportions:

[0025] 640g of Sophora flavescens, 320g of Baibu, 320g of Cnidium, 320g of Agrimony, 320g of Purple Pearl Leaf, 10g of alum, 5g of borneol, 10g of camphor, 60g of boric acid;

[0026] Take the above nine medicinal materials, take Sophora flavescens, Baibu, Cnidium, Agrimony, Agrimony, and add 8 times the amount of water to decoct three times. The first and second times are 2 hours each, and the third time is 1 hour. Filtrate hot, concentrate the filtrate to a clear paste with a relative density of 1.08-1.10 (25°C), add 95% ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter the supernatant, and recover ethanol from the filtrate, Prepare the medicinal material extract for later use, take another 150g carbomer, add appropriate amount of water to swell, grind the alum and boric acid into the fines...

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PUM

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Abstract

A Chinese medicine in the form of gel for treating the gynopathic inflammation is prepared from flavescent sophora root, stemona root, cnidium fruit, agrimony and beautyberry leaf through decocting three times, collecting decoction, filtering, concentrating, adding alcohol, laying aside, taking supernatnat, filtering, recovering alcohol, mixing it with the fine powder of alum and boric acid, the alcohol solution of borneol and camphor, gel matrix and water, stirring, regulating pH=4-6, and stirring.

Description

technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a kind of Baicaofuyanqing gel, and also relates to a preparation method thereof. Background technique [0002] At present, the dosage forms of heat-clearing and detoxifying, insecticidal and antipruritic, and stasis-removing and astringent varieties are relatively single, usually lotions, suppositories, effervescent tablets or foams, etc. The lotion stays in the affected part for a short time, has poor bactericidal effect, and is inconvenient to apply; and Although the suppository stays in the vagina for a long time, it is easy to flow out from the vagina after melting and pollute the clothes. At the same time, because it contains a large amount of glycerin, it is easy to cause bladder edema and a strong foreign body sensation in the vagina; The mucous membrane is irritating to a certain extent; the fluorine-containing propellant in the foam can easily cause the vagin...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K33/06A61K33/22A61K31/045A61K9/00A61P15/00
Inventor 杨伟荣
Owner 杨伟荣
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