Method and system for registration, identifying and processing of drug specific data

Abstract

The invention relates to a method for registration, identifying and processing of drug specific data and for making drugs available to individual patients without severe adverse drug reactions. The invention relates also to a system for carrying out such a method. According to the present invention, the system comprises a master database correlating patterns of gene expression and genetic polymorphisms with drug-induced i.e. drug-related adverse effects and drug structure. The system also comprises a predictive data-tool. In this tool the structural and genetic fingerprints predictive for adverse effects in individual patients due to treatment with a selected drug are stored. The method according the invention is characterized in that the master database being coupled to the database of the predictive data-tool in such a way that a user of the system can develop and carry out different screening approaches either to verify the sociability of drugs for a specific selected category of patients or to search a specific drug for a selected category of patients which do not have adverse drug reactions or to make risk-analyses.

Description

[0001] 1. Field of the Invention[0002] The invention relates to a method for registration, identifying and processing of drug specific data and for making drugs available to individual patients avoiding adverse drug reactions (ADR). The invention relates also to a system for carrying out such a method.[0003] 2. Description of the Prior Art[0004] Current methods and systems being used for access control of drug delivery are not sufficiently reliable and secure for the routine medical treatment of patients with drugs.[0005] Thus, more than 2 million adverse drug reactions occur annually in the United States. An analysis of 39 prospective studies (JAMA 1998, 279, 1200-1205) shows that in 1994 2,216,000 patients have been hospitalised with adverse drug reactions, 106,000 patients of them with fatal outcome.[0006] Recent examples of drugs affected by severe ADR include the following:1 Drug Reaction Troglitazone Rezulin Anti-diabetes type II drug; severe liver toxicity, unexpected deaths;...

AI Technical Summary

Benefits of technology

[0013] means for coupling the master database and the predictive tool in such a way that electronically prospective theragenomic information can be developed which allows the safe use of a given drug or a safe drug therapy, which is, with high probability, free of adverse drug reactions in an individual patient, wherein

Problems solved by technology

Current methods and systems being used for access control of drug delivery are not sufficiently reliable and secure for the routine medical treatment of patients with drugs.

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