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Method of treating erythematous papules

a technology of erythematous papules and laser treatment, which is applied in the field of laser treatment of erythematous papules, can solve problems such as dermatological imperfections, and achieve the effects of promoting the growth of dermal collagen, reducing the incidence, severity and appearance of erythematous papules, and reducing the severity of erythematous papules

Inactive Publication Date: 2005-03-10
BERNSTEIN ERIC F
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0004] The present invention is directed to a method for treating erythematous papules as well as the skin between the papules. Acne-prone skin is erythematous not only in areas of active acne, but also in areas where acne has previously occurred, or where it is about to occur. In addition, acne lesions often have excess melanin pigment in the area where inflammation has caused deposition of excess epidermal melanin in the superficial dermis and in the area of the hair follicles. In one aspect, the method of the present invention comprises irradiating the skin to be treated with light (electromagnetic radiation) having a wavelength selected such that it is preferentially absorbed in a dermal region of the skin including a melanocyte layer of the epidermis and a region of superficial vasculature immediately below the melanocyte layer. The light is delivered at a fluence sufficient that the preferential absorption thereof stimulates a wound healing response in the dermal region without causing a wound. The wound healing response promotes growth of dermal collagen, and other extracellular matrix and inflammatory compounds, in the area surrounding the hair follicles. This reorganization of dermal collagen affects the structure and function of sebaceous glands, altering their activity and reducing the incidence, severity and appearance of erythematous papules such as, but not limited to, rosacea, and both inflammatory and comedonal acne.

Problems solved by technology

While such imperfections may not be considered as aesthetically unpleasant or inconvenient, they are nonetheless dermatological imperfections.

Method used

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Embodiment Construction

[0011] The method of the present invention relies on using laser radiation to stimulate the skin's wound healing responses. The laser radiation wavelength and the laser radiation fluence are selected such that the wound healing responses are stimulated without actually inflicting a wound. The wound healing responses promote growth or production of dermal collagen. The term “wound” here is meant to define an open wound, blister or any other effect which would be manifest in, or lead to, necrosis of tissue.

[0012] The biology of wound healing is a very complex process. Cytokines released by the vascular endothelial cells and epidermal keratinocytes are responsible for initiating the increased production of collagen. This takes place in a series of interrelated steps via the resident cells of the dermis. These elements lie in the uppermost regions of the skin. By selecting a wavelength of laser radiation in a range between about 525 and 550 nm, the wound healing response is concentrate...

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Abstract

Methods for treating erythematous papules by irradiating skin with light having a wavelength between about 525 nanometers and 550 nanometers are provided.

Description

INTRODUCTION [0001] This patent application is a continuation-in-part of U.S. application Ser. No. 09 / 738,523 filed Dec. 15, 2000, which is herein incorporated by reference in its entirety.FIELD OF THE INVENTION [0002] The present invention relates in general to laser treatment of dermatological imperfections. The invention relates in particular to non-ablative laser treatment of erythematous papules such as acne and rosacea. BACKGROUND OF THE INVENTION [0003] The aesthetic treatment of abnormal dermatological conditions such as acne and rosacea has hitherto involved using topical treatments, physical methods of pore extraction, and oral antibiotics as well as oral retinoids. Prior-art treatments and investigations of treatments have been concentrated primarily on the use of antibiotics, steroid therapies, and low intensity blue light for photochemical therapy. Treatment of dermatological imperfections such as acne and rosacea has received relatively little investigative attention. ...

Claims

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Application Information

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IPC IPC(8): A61B18/20
CPCA61B18/203A61B2018/0047A61B2018/00452
Inventor BERNSTEIN, ERIC F.
Owner BERNSTEIN ERIC F
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