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Biocidic household cleansing materials

a technology of biocide and household cleaning, applied in the field of household cleaning materials, can solve the problems of biofilm formation in drinking water systems, water distribution conduits, water cooling towers for air conditioning systems, and food spoilage, and achieve the effect of effectively disrupting the ph homeostis and/or electrical balance, and efficiently preserving the ph of the ltcs' environmen

Inactive Publication Date: 2010-06-03
OPLON
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0025]It is another object of the invention to disclose the household cleaning materials as defined above, wherein the device comprising two or more, either two-dimensional (2D) or three-dimensional (3D) PSSs, each of which of the PSSs consisting of materials containing highly dissociating cationic and / or anionic groups (HDCAs) spatially organized in a manner which efficiently minimizes the change of the pH of the LTC's environment; each of the HDCAs is optionally spatially organized in specific either 2D, topologically folded 2D surfaces, or 3D manner efficiently which minimizes the change of the pH of the LTC's environment; further optionally, at least a portion of the spatially organized HDCAs are either 2D or 3D positioned in a manner selected from a group consisting of (i) interlacing; (ii) overlapping; (iii) conjugating; (iv) either homogeneously or heterogeneously mixing and (iv) tiling the same
[0057]It is another object of the invention to disclose a method for avoiding development of LTC's resistance and selecting over resistant mutations. The method comprising steps of: obtaining at least one household cleaning materials as defined in any of the above; contacting the PSS with an LTC; and, effectively disrupting the pH homeostasis and / or electrical balance within the LTC such that development of LTC's resistance and selecting over resistant mutations is avoided, while efficiently preserving the pH of the LTC's environment and patient's safety.

Problems solved by technology

The presence of these organisms can result in spoilage of food, detrimental environmental impact and in some cases, to direct infection.
For example, drinking water systems and water distribution conduits as well as water cooling towers for air conditioning systems are well-known to pose public health risks from biofilm formation, as episodic outbreaks of infections.
Biofilms are also a constant problem in food processing and storage environments.
However, alcohol may not be effective against hepatitis A and other non-lipophilic viruses, depending on the alcohol concentration and the amount of time that viruses are exposed to the alcohol.
The agent possesses reasonable activity against mycobacteria and Candida species, but it has limited activity against filamentous fungi.
However, virus that is transferred from nose to tissue without passing through the active layer is still infectious.
It has not been established whether this product can reduce transmission of respiratory infections in households.
Although these strategies have been verified in aqueous solutions containing bacteria, they would not be expected to be effective against airborne bacteria in the absence of a liquid medium; this is especially true for release-based materials, which are also liable to become impotent when the leaching antibacterial agent is exhausted.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0094]Antibacterial Laundry Softener

[0095]Material and methods A regular household laundry session at home (30° C.) performed with modified softener as described above and tested against standard softener by recording bacterial growth of natural flora by placing samples of wet fabrics on agar plates, at the various intervals. Laundry was kept wet in the washing machine, at room temperature, until sampled.

[0096]Results

[0097]Reference is made to FIG. 1, illustrating the bacterial counts in fabric samples taken from regular softener treated laundry and modified softener treated laundry.

[0098]The results are presented in FIG. 1 showing 3-orders of magnitude decrease in bacterial count at time zero (right after the laundry session) and 12 hours thereafter between regular softener treated laundry and modified softener.

example 2

[0099]Antibacterial Laundry Additives

[0100]Material and Methods

[0101]Tow pieces of cotton (sample 1 & 2) were boil-washed with standard household detergents.

[0102]Following the washing stage, 50 milliliters of the spray formulations of Comp.4 above were added in the final rinse stage. Two other pieces of cotton (sample 3 & 4) were boil-washed in a standard manner and served as controls. 30 min after the wash the samples were tested for natural bacterial flora as described above. Following that test the samples were kept in open air in a very contaminated room for several days and sampled periodically.

[0103]Results

[0104]Reference in now made to FIG. 2, presenting bacterial counts (CFU) in cloth samples 0.5 and 24 hrs after boil-wash with or without antibacterial laundry additive; and to FIG. 3, presenting bacterial counts (CFU) in cloth, samples 0.5, 24, 48 hrs and 9 days after boil-wash with or without antibacterial laundry additive.

[0105]The results are summarized in the following ...

example 3

[0106]Antibcterial Spray

[0107]Material and Methods

[0108]A part of a humid surface (a marble top near the sink in a public toilet) was treated with a spray solution of Comp.1 and sampled once every hour for 4 consecutive hours, for bacterial content by swab sampling and spreading on a Petri dish.

[0109]Results

[0110]Reference in now made to FIG. 4, showing bacterial counts (CFU) in samples taken from sprayed and unsprayed marble surface.

[0111]Results in Table 2 and FIG. 4 below show a difference of 3-orders-of-magnitude in bacterial population between spray-treated and untreated marble surface.

TABLE 2Bacterial counts (CFU) in samples takenfrom sprayed and unsprayed marble surfaceTime afterSprayed surfaceUnsprayed surfacetreatment (h)(CFU)(CFU)13.9 × 1033.5 × 10623.1 × 1032.4 × 10632.7 × 1036.8 × 10643.9 × 1039.2 × 105

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Abstract

The present invention discloses household cleaning materials comprising at least one insoluble proton sink or source (PSS) and to method for utilizing the PSS as a biocidic agent. The household cleaning materials are provided useful for killing living target cells (LTCs) or otherwise inhibiting LTCs growth, disrupting vital intracellular processes and / or intercellular interactions of the LTC upon contact. The household cleaning materials consisting of at least one PSS, comprises, inter alia, (i) proton source or sink providing a buffering capacity; and (ii) means providing proton conductivity and / or electrical potential. The PSS is effectively disrupting the pH homeostasis and / or electrical balance within the confined volume of said LTC and / or disrupting vital intercellular interactions of said LTCs while efficiently preserving the pH of said LTCs' environment.

Description

FIELD OF THE INVENTION[0001]The present invention pertains to household cleaning materials inhibiting microbial growth. More specifically, the invention relates to household cleaning materials that comprise means for killing living target cells, or otherwise disrupting vital intracellular processes and / or intercellular interactions of said cells upon contact.BACKGROUND OF THE INVENTION[0002]The present invention relates to new compositions and materials exhibiting strong antimicrobial properties, for use in household cleaning in wipes, sprays, soaps, cleaning solutions, gels, creams, deodorants, fabric treatment materials etc.[0003]Microorganisms like bacteria, fungi, molds etc. are ubiquitous in the human environment. The presence of these organisms can result in spoilage of food, detrimental environmental impact and in some cases, to direct infection.[0004]Biofilm formation has widespread health implications. Any system that provides an interface between a surface and a fluid has ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A01N61/00A01N25/00C08F112/08
CPCA01N61/00C11D17/049C11D3/48A61L2/22Y10T442/10Y10T442/60
Inventor BUKSHPAN, SHMUELZILBERSTEIN, GLEB
Owner OPLON
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