40results about How to "Efficiently disrupted" patented technology

Chronic otitis media and other bacterial ear conditions may be treated by applying a solvating system containing a metal ion sequestering agent and surfactant to a bacterial biofilm in the middle or inner ear. The solvating system disrupts the biofilm and aids in its removal.

The present invention relates to a method for the recovery of poxviruses, in particular modified Vaccinia virus Ankara (MVA), from infected cells. According to the present invention the virus-infected cells are subjected to a high-pressure homogenization to obtain a virus containing homogenate. The virus containing homogenate can be subjected to at least one purification step to obtain apoxvirus-enriched fraction. The invention further relates to the virus containing fraction and the virus containing homogenate obtained by the method according to the present invention.

The present invention relates to an agent having activity in the treatment of a tissue disruption. In particular the present invention relates to a composition comprising an effective amount of an active fraction having tissue healing properties

The invention aims at providing a method of producing a poly-3-hydroxyalkanoic acid,which comprises carrying out a physical disruption treatment of a suspension of poly-3-hydroxyalkanoic acid-containing microbial cells with adding an alkali thereto either continuously or intermittently and, thereafter, separating the poly-3-hydroxyalkanoic acid.

Disclosed is a roof spoiler that effectively disrupts the attached flow of wind upon a roof surface. This spoiler has a stowed position, whereby it is almost completely out of the view of passersby. It also has a deployed position, wherein a barrier is projected vertically, or substantially vertically, so as to disrupt the flow of air over the roof surface. This spoiler utilizes a hinged design to move between these two positions. The spoiler is specially designed to operate in conjunction with a gutter mounted along the leading edge of the roof. In the stowed position, a portion of the spoiler covers the open gutter. In one embodiment, the spoiler is L-shaped to facilitate its stability in the deployed position.

Disclosed is a roof spoiler that effectively disrupts the attached flow of wind on a roof surface. Preferably, the spoiler is specially designed for installation with a gutter mounted on the roof fascia or along the leading edge of the roof. This spoiler utilizes a hinged design to move between two operating positions. The first position is a stowed position, whereby the spoiler extends beyond the gutter and is designed to be nearly invisible to passersby. In the stowed position, a portion of the spoiler covers the outer edge of the gutter (if present). A second portion of the spoiler may extend outward from the gutter. The second position is a deployed position, wherein a barrier is projected vertically, or substantially vertically, so as to disrupt the flow of air over the roof surface. In one embodiment, the spoiler rests upon the roof covering when in the deployed position. In another embodiment, the spoiler rests near or against the gutter or holding bracket. In one embodiment, a bracketing system, or support structure, is placed around an existing gutter. The roof spoiler is then pivotally attached to this support structure. In another embodiment, the support structure attaches directly to the gutter.

The present invention relates to a cell lysis apparatus and a manufacturing method thereof, and more particularly, to a cell lysis apparatus, which mechanically performs cell lysis, and a manufacturing method thereof. The cell lysis apparatus includes: an inlet port through which fluid containing cells is supplied; a fluid channel defining a passage through which the cell containing fluid supplied from the inlet port flows; a nano blade array including a plurality of nano blades having pointed leading ends and arranged such that the pointed leading ends of the nano blades are oriented in a direction of the fluid supplied through the inlet port to disrupt the cells passing therethrough; and an outlet port through which the disrupted cells and the fluid are discharged.

Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.

Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.

This disclosure relates to methods for promoting bone formation or reducing bone destruction. This disclosure also relates to methods for promoting the recruitment of mesenchymal stem cells (MSC) to a local site of injury or surgical intervention in bone to promote healing. In addition, this disclosure relates to methods for reducing or preventing mineral formation or bone growth, or reducing bone mass. The methods disclosed herein are useful for treating conditions such as osteoradionecrosis.

Systems and methods of preventing or reducing crop damage from pests are provided. In one embodiment, the method comprises: a) applying a mating disruption tactic to a field plot; and b) disrupting expression of one or more target genes in one or more pests, wherein crop damage is reduced in the field plot. In another embodiment, the method comprises applying an attract-and-kill tactic to a field plot, wherein said attract-and-kill tactic comprises: a) applying one or more semiochemicals or factors; and b) disrupting expression of one or more target genes in one or more pests, wherein said disruption is capable of killing the one or more pests, wherein crop damage is reduced in the field plot.