Composition and method for the oxidative consumption of salivary biomolecules

Abstract

The composition and method for the use of stabilized chlorine dioxide as an antimicrobial agent against oral microorganisms for the treatment and prevention of halitosis and prevention of oral diseases through its oxidative consumption and inactivation of volatile sulfur compounds and their amino acid precursors is disclosed. Preferred concentrations of stabilized chlorine dioxide in this invention are in the range of 0.005% to 2.0% (w/v).

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]The present application includes subject matter disclosed in and claims priority to a provisional patent application entitled “Oxidative Consumption of Salivary Biomolecules” filed Feb. 13, 2009 and assigned Ser. No. 61 / 152,336, assigned to the present assignee.FIELD OF THE INVENTION[0002]The present invention relates to the oxidative consumption of salivary biomolecules, in particular, it relates to the generation of chlorine dioxide for antibacterial affects in the oral cavity with a stabilized chlorine dioxide composition.BACKGROUND OF INVENTION[0003]Oral disease refers to a number of generally preventable conditions of the mouth with a variety of causes. Plaque is the most recognizable precursor to oral disease. It is the biofilm that forms on teeth within hours after they are cleaned. The main mineral component of teeth is hydroxyapatite (HAP) and when teeth are cleaned, HAP becomes exposed to the oral environment. Salivary proteins ...

AI Technical Summary

Benefits of technology

[0025]Stabilized chlorine dioxide has a beneficial effect of tending to prevent a number of factors of oral disease, both by eliminating the bacteria that cause them and also by oxidizing molecules associated with them using a solution in the form of a wash, rinse, soak, paste, gel, aerosol spray, or other suitable delivery system.

Problems solved by technology

The patent describes the weak bonds between some amino acids, like cysteine, leading to susceptibility to being destroyed by oxidative consumption.

While prior art teaches various compositions of stabilized chlorine dioxide relative to oral health, they do not teach a method of stabilized chlorine dioxide to oxidatively consuming salivary biomolecules to produce antimicrobial affects for the reduction of growth and development of oral bacteria and microorganisms concerned with halitosis and oral disease by the generation of chlorine dioxide.

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