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Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology

a technology of proprioception feedback and functional mitigation, applied in the field of surgical paradigm for limb amputation, can solve the problems of acute high stress in the soft tissue, lack of technology to restore proprioception feedback, and limited development of implantable devices, so as to improve the fidelity of perceived joint position, enhance human physicality, and restore the effect of natural muscle control function

Pending Publication Date: 2022-02-03
MASSACHUSETTS INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patent describes a method and system for treating limb pathologies and enhancing human physicality. It can preserve post-amputation function in the residuum and restore natural muscle control function in paralyzed or weakened limbs. The system provides repeatable control of each muscle in the agonist / antagonist pair, improving fidelity of the perceived joint position. It can also reduce pain and discomfort during prosthetic socket loading by transmitting load more evenly across load-bearing soft tissue of the residual limb. The functional stimulation system of the invention overcomes the problem of imprecise muscle stimulation and ensures accurate position information is communicated to the prosthesis user. This invention has many advantages for treating limb pathologies and enhancing human physicality.

Problems solved by technology

Further, there is currently no technology to restore proprioceptive feedback to thereby communicate joint and / or actuator state from a prosthesis to a patient.
As the residuum is distally loaded, the soft tissue at the distal end of the residual limb is compressed against this small, rigid cross-section of the residual tibia, resulting in acute high stresses in the soft tissue.
Typically, development of implantable devices is currently limited by the ability to transmit power and information across the skin membrane.
Wireless transmission of power is inherently inefficient, and communication often is hampered by bit-rate throttling.
These obstacles are amplified as the wireless communication distance increases.
However, concerns about infection have hindered development of wired solutions.
Neuromuscular pathologies are often the result of damaged neural pathways between movement centers in the central nervous system and the skeletal muscles they control.
Whether through dysfunctional contraction dynamics or muscular paralysis, this breakdown in communication renders muscles unable to produce natural movement, reducing quality of life for millions currently suffering from neuromuscular pathologies.

Method used

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  • Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology
  • Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology
  • Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology

Examples

Experimental program
Comparison scheme
Effect test

embodiment 1

oupling of Agonist-Antagonist Residual Muscle Pairs Across

Surgically Constructed Sliding Surfaces

[0070]A first embodiment of this invention is a method that constructs an architecture in the residual musculature that can be used to provide proprioceptive feedback from an external limb prosthesis.

[0071]In this embodiment, the invention includes a method for reconstructing the biological proprioceptive feedback paradigm in a subject, such as a person, with limb amputation. The method includes mechanically linking the distal ends of residual musculature across a sliding surface, so that contraction of the agonist muscle causes stretching of the antagonist and vice versa. By allowing such an agonist-antagonist interaction, the antagonist muscle that is stretched provides length, speed and force proprioceptive feedback to the amputee user, via each muscle nerve supply, to communicate muscle action and joint movement. Alternatively, when the antagonist muscle contracts, the agonist muscle...

embodiment 2

sseointegrated Sliding Surface for Mechanically-Coupled

Agonist-Antagonist Muscle Pairs

[0083]Osseointegration is a proven methodology that has existed for years in the fields of medical dentistry, orthopedic surgery, and prosthetic technology. The core principle involves insertion of a biologically inert synthetic material into porous bone tissue. The body's natural reaction to the foreign material causes integration of the living tissue and the synthetic insert, forming a robust mechanical bond. In this embodiment of the invention, sliding surfaces for mechanically-coupled agonist-antagonist muscle pairs are secured to the distal end of a bone, such as a tibia or a fibula, by osseointegration. Exemplary versions of this embodiment of the invention include:

[0084]1. Forming rings. Muscle couplings, whether made of muscle, tendon, or a synthetic material, slide through rings formed by osseointegration into the distal end of the bone, which thereby inherently prevent dislodgement of the...

embodiment 3

sseointegrated Distal Load-Bearing Attachment

[0087]Another embodiment of the method of the invention includes embedding an implant in the residual limb to broaden the load-bearing surface of the distal residuum and thereby spread relatively high compression forces across a larger load-bearing surface.

[0088]In this embodiment of the method of the invention, an extension (either biologic or synthetic) is embedded in the skeletal system to increase comfort in compressive distal load-bearing. Two examples of this embodiment of the invention are described below:

[0089]1. Osseointegrating a structure that is shaped geometrically to increase load-bearing surface area. Concentrated areas of high pressure are eliminated by increasing the surface area through which the compressive load is transmitted. FIG. 14 shows an example of a system formed by this embodiment of the method of the invention. FIGS. 15 and 16 show examples of how the system may be combined with a synthetic sliding surface att...

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Abstract

Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.

Description

RELATED APPLICATION[0001]This application is a divisional of U.S. application Ser. No. 16 / 068,531, filed Jan. 6, 2017, which is the U.S. National Stage of International Application No. PCT / US2017 / 012553, filed Jan. 6, 2017, which designates the U.S., published in English, and claims the benefit of U.S. Provisional Application No. 62 / 276,422, filed on Jan. 8, 2016. The entire teachings of the above applications are incorporated herein by reference.BACKGROUND OF THE INVENTION[0002]Generally, the current clinically-accepted surgical paradigm for limb amputation servers discarded tissue with no thought of potential use in neural prosthetic control paradigms, and has not changed substantially in over a century. Further, there is currently no technology to restore proprioceptive feedback to thereby communicate joint and / or actuator state from a prosthesis to a patient.[0003]Biological feedback of muscle or joint state (position and its derivatives) depends on a differential stretch signal...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61F2/72A61N1/36A61F2/64A61F2/80A61H3/00A61N5/06
CPCA61F2/72A61N1/36003A61F2/64A61F2002/7887A61H3/00A61N5/0622A61F2/80A61N1/0551A61N1/36017A61F2002/5059A61F2002/6827A61F2002/6872A61F2002/6881A61F2002/704A61F2002/705A61H2201/5058
Inventor HERR, HUGH M.CLITES, TYLERMAIMON, BENJAMINZORZOS, ANTHONYCARTY, MATTHEW J.DUVAL, JEAN-FRANCOISSRINIVASAN, SHRIYA SRUTHI
Owner MASSACHUSETTS INST OF TECH
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