4 results about "Home testing" patented technology

A disposable cartridge for a home testing device includes a housing, a fluidic component including at least an input port, at least a flow channel, and a sensor chamber communicatively connected to a reader device, at least a reagent supply component having at least a well containing at least a reagent, a sample source containing a biological sample, and at least a pipette is movable relative to the reagent supply component and the fluidic component between a reagent collection position wherein the distal port is inserted into a well of the at least a well and an ejection position wherein the distal port is inserted into the at least an input port, and the at least a pipette is configured to provide the at least a reagent and the biological sample to the at least an input port.

The subject invention relates to a skin-temperature operated iNAAT for at-home testing, called CRISPR-regulated one-pot Recombinase Polymerase Loop-mediated Amplification (CoRPLA) with rationally designed loop primers that enhance isothermal amplification, specifically trigger Cas12 cis-cleavage for in-situ amplicon depletion and initiate concurrent Cas12 trans-cleavage-based signal amplification, to eliminate amplicon-related cross-contamination and enables semi-quantitative response to the initial target amount with sub-attomolar sensitivity (0.5 cps / μL).

The invention discloses a device for collecting exhaled air condensate and a respiratory virus home detection method, the device comprises a main body, the main body comprises a semiconductor refrigeration module, an airflow channel at least partially arranged in the semiconductor refrigeration module, and a disposable unit detachably connected to an inlet of the airflow channel; a label-free electrochemical sensor for receiving the exhaled air condensate sample from the body; and the analysis module is an application program loaded on electronic equipment, a machine learning algorithm is built in the analysis module, and the analysis module is in communication connection with the unmarked electrochemical sensor and is configured to receive the electric signals of the unmarked electrochemical sensor and perform automatic analysis, comparison and result output. According to the invention, rapid, stable and non-invasive sample collection without pre-cooling can be realized, and rapid detection of respiratory viruses can be completed in a home environment.

The present invention relates to an iNAAT, referred to as CRISPR-regulated one-pot recombinase polymerase loop-mediated amplification (CoRPLA), for skin temperature manipulation for home detection, with reasonably designed loop primers that enhance isothermal amplification, specifically trigger Cas12 cis-cleavage for in situ amplicon depletion and initiate simultaneous Cas12 trans-cleavage-based signal amplification, in particular Cas12 cis-cleavage-based signal amplification, for in situ amplification. The method can be used to eliminate amplicon-associated cross contamination and can make a semi-quantitative response to an initial target amount with sub-attomole sensitivity (0.5 cps / [mu] L).