The invention provides a toilet flushing system based on negative pressure drainage, the toilet flushing system includes a mechanical linkage device, a water tank, a wash basin, a wastewater treatment tank, a water inlet pipe of the water tank, a valve, a buoyancy rod, a floater, a plug, a diaphragm, a piston, a gas storage chamber, a contraction section, one one-way valve, a guide pipe, another one-way valve, a throat pipe, a siphon bend, a divergent section, a drainage pipe, and a toilet. The mechanical linkage device is connected with the water tank and a Venturi pipe, the water tank includes a tank body A and a tank body B, and the tank bodies of A and B are equipped with purified recycled water for life and tap water respectively. The throat of the Venturi pipe is connected with the siphon bend of the toilet. When the mechanical linkage device is triggered, the water of the tank body A flushes the toilet, at the same time, a jet flow is formed at the throat, and the momentum of the dirt discharged with the drainage is increased. Through the mixture design of the siphon and the Venturi pipe, the siphonage is formed when the flushing water is not large, the piston is mainly driven by the linkage device to pressurize the gas in the gas storage chamber, and a high velocity flowing fluid is formed in the throat so as to produce the adsorption effect.