13 results about "N-Octanoic acid" patented technology

The present application relates to the technical field of fine chemical synthesis, and in particular to an efficient preparation process of octanoyl hydroxamic acid, which comprises the following preparation steps: S1, preparation of ethyl n-octanoate: 90-110 parts by weight of n-octanoic acid and 35-40 parts by weight of ethanol are mixed, and then a solid acid catalyst is added, and the mixture is heated to reflux for reaction for 2.5-3 hours, filtered to obtain a precipitate and a filtrate, and the filtrate is decompressed and distilled to obtain ethyl n-octanoate; S2, preparation of octanoyl hydroxamic acid: 0.4-0.6 parts by weight of sodium acetate and 0.2-0.4 parts by weight of sodium carbonate are added to water, stirred until dissolved, ethanol is added, and after stirring, 24-32 parts by weight of hydroxylamine and ethyl n-octanoate prepared in S1 are added to react to obtain octanoyl hydroxamic acid; the process has the advantage of improving the reusability of the solid acid catalyst.

The invention relates to the technical field of gas leak detection agents, and provides a micron bubble leak detection agent and a preparation method and application thereof. The micron bubble leak detection agent is composed of a component A and a component B, wherein the component A comprises the following components in parts by weight: 40-50 parts of deionized water, 2-4 parts of n-caprylic acid, 1-1.5 parts of a foaming agent, 0.1-0.2 part of a corrosion inhibitor, 0.05-0.08 part of sodium polyacrylate and 0.02-0.04 part of a chelating agent; the component B is prepared from the following components in parts by weight: 40 to 50 parts of deionized water, 0.05 to 0.1 part of sodium carboxymethyl cellulose, 0.05 to 0.1 part of xanthan gum, 0.4 to 0.8 part of polyhydric alcohol, 0.2 to 0.4 part of octanol and 0.3 to 0.5 part of an auxiliary agent; the auxiliary agent comprises anionic polyacrylamide and hydrolyzed polyacrylonitrile sodium salt in a mass ratio of 2: (1-2). According to the technical scheme, the problem of insufficient foam stability of the gas leak detection agent in the prior art is solved.

This application relates to the field of fine chemical synthesis technology, and in particular to an efficient preparation process of octanoyl hydroxamic acid, which includes the following preparation steps: S1. Preparation of ethyl octanoate: Mix 90 - 110 parts by weight of octanoic acid and 35 - 40 parts by weight of ethanol, then add a solid acid catalyst, heat under reflux for 2.5 - 3 h, filter to obtain a precipitate and a filtrate, and distill the filtrate under reduced pressure to obtain ethyl octanoate; S2. Preparation of octanoyl hydroxamic acid: Add 0.4 - 0.6 parts by weight of sodium acetate and 0.2 - 0.4 parts by weight of sodium carbonate to water, stir until dissolved, add ethanol, stir, then add 24 - 32 parts by weight of hydroxylamine and the ethyl octanoate prepared in S1, and react to obtain octanoyl hydroxamic acid; it has the advantage of improving the reusability of the solid acid catalyst.

This invention relates to an additive manufacturing method for strain rate-enhanced composite gels, comprising: a) polymerizing silicone oil, boric acid, and octanoic acid at high temperature to prepare a shear-hardening gel; b) introducing the shear-hardening gel into a polyvinyl alcohol aqueous solution and adding chitosan particles, followed by ball milling to obtain a composite gel precursor; c) printing the composite gel precursor using pneumatic extrusion combined with a triaxial motion control system, and then obtaining the composite gel through freeze-thaw treatment. This composite gel precursor is propelled from the nozzle by air pressure in a pneumatic extruder, and the triaxial motion control system enables the deposition of arbitrary two-dimensional patterns and the stacking of three-dimensional structures, overcoming the limitations of traditional strain rate-enhanced composite gels formed by molding and injection molding methods, and endowing it with greater molding freedom and higher molding precision in additive manufacturing.

This invention relates to the field of gas leak detection agents, and proposes a micron-sized bubble leak detection agent, its preparation method, and its application. The micron-sized bubble leak detection agent consists of component A and component B. Component A includes the following components by weight: 40-50 parts deionized water, 2-4 parts n-octanoic acid, 1-1.5 parts foaming agent, 0.1-0.2 parts corrosion inhibitor, 0.05-0.08 parts sodium polyacrylate, and 0.02-0.04 parts chelating agent. Component B includes the following components by weight: 40-50 parts deionized water, 0.05-0.1 parts sodium carboxymethyl cellulose, 0.05-0.1 parts xanthan gum, 0.4-0.8 parts polyol, 0.2-0.4 parts octanol, and 0.3-0.5 parts additives. The additives include anionic polyacrylamide and hydrolyzed sodium polyacrylonitrile in a mass ratio of 2:1-2. This technical solution solves the problem of insufficient foam stability in gas leak detection agents in related technologies.

The invention discloses an interactive response layered superlattice nanoprobe as well as a synthesis method and application thereof, and belongs to the technical field of nanomaterials and biosensing. The nanoprobe is synthesized through a ligand regulation and control self-assembly strategy, specifically, a platinum source, n-caprylic acid and molybdenum hexacarbonyl are mixed and heated for a reaction, and after the reaction is finished, aftertreatment is conducted to obtain the interactive response layered superlattice nanoprobe. The nanoprobe has a highly-ordered layered superlattice structure, and can generate synergistic change of structure and catalytic activity under different H2O2 concentrations, so that specific interactive response to H2O2 is realized. The nanoprobe is controllable in synthesis process and stable in structure, the interactive response performance of the nanoprobe provides core material support for threshold type detection of biomarkers, the technical problems that a traditional nanomaterial is single in response to substrate concentration change and insufficient in sensitivity are solved, and the nanoprobe has important application value in the fields of biosensing, clinical detection and the like.

The invention discloses a device and a method for continuously synthesizing capryloyl chloride by using a scraper film reactor. The device comprises a reaction kettle, vacuumizing equipment, a stirrer, a feeding assembly and a discharging assembly, an interlayer is arranged on the inner wall of the reaction kettle and is used for introducing a heat-conducting medium; the vacuumizing equipment is arranged on the reaction kettle and is communicated with the inner cavity of the reaction kettle; the stirrer is mounted in the reaction kettle, a plurality of scrapers are mounted at the output end of the stirrer, and the feeding assembly is mounted at the top of the reaction kettle and communicated with an inner cavity of the reaction kettle; the feeding assembly is used for adding liquid n-caprylic acid and thionyl chloride into the reaction kettle; the discharging assembly is mounted at the bottom of the reaction kettle and is communicated with the inner cavity of the reaction kettle. According to the invention, the principle of scraper type film evaporation is utilized, so that high-purity and high-yield capryloyl chloride products are efficiently synthesized, hydrogen chloride and sulfur dioxide gas generated in the reaction process can be discharged and recycled, the green and environment-friendly process requirements are met, and the purity and yield of the products are improved.

The invention discloses structural lipid for improving cognitive impairment of old people and a preparation method of the structural lipid. Immobilized lipase is filled into a continuous flow bio-enzyme catalytic reaction column, and nitrogen charging treatment is carried out; the preparation method comprises the following steps: uniformly stirring and mixing sn-2-site triglyceride with DHA mass content of 65% or above and n-caprylic acid to obtain a reaction solution; and pumping the reaction liquid into a continuous flow bio-enzyme catalytic reaction column to obtain mixed lipid, and carrying out deacidification and dehydration treatment to obtain the structural lipid. According to the invention, the humic acid peculiar smell of n-caprylic acid and the fishy smell of DHA are obviously improved, and the flavor acceptance is improved; meanwhile, the defects of strong irritation of high-dose n-caprylic acid, poor oxidation stability of DHA, low absorption rate and the like are effectively overcome, and the functional safety and the quality stability of the product are enhanced. The structural lipid shows a synergistic effect in the aspect of improving cognitive impairment, is suitable for nutrition intervention of aging or neurodegenerative diseases, and has a good application prospect.

The invention discloses a composition for improving oral bioavailability of ursolic acid and a preparation method thereof, and the method comprises the following steps: mixing a hydrogen acceptor and a hydrogen donor to obtain a eutectic solvent; the hydrogen acceptor is menthol; the hydrogen donor is butyric acid, hexanoic acid, n-caprylic acid, capric acid or oleic acid; mixing the eutectic solvent with ursolic acid, and swirling at 60 DEG C; the molar ratio of the hydrogen acceptor to the hydrogen donor is 2: 1, 1: 1 or 1: 2. The invention solves the problem of low bioavailability of terpenoids in the existing apple peel extract. When the amount-of-substance ratio of menthol to capric acid is 1: 2, the bioavailability of ursolic acid in a cell experiment is up to 18.6%, the total cell absorption rate is up to 82%, the cell uptake rate is up to 19.3%, and the cell secretion rate at 4 hours is up to 61.99%; the bioaccessibility of ursolic acid in an in-vitro experiment reaches up to 23%.

The invention relates to a refrigerating machine oil composition, a preparation method and an application of the refrigerating machine oil composition in cryosleep refrigeration equipment. The refrigerating machine oil composition comprises base oil, an anti-wear agent, an antioxidant, a metal deactivator and an acid capturing agent. The fluorine-containing cyclobutyl synthetic ester disclosed by the invention is generated by esterification of n-caprylic acid (long-chain carboxylic acid) and (3, 3-difluorocyclobutyl) methanol (fluorine-containing cyclobutyl alcohol), so that a four-membered ring rigid framework of (3, 3-difluorocyclobutyl) in a molecular structure of the fluorine-containing cyclobutyl synthetic ester can destroy regular stacking of molecular chains; moreover, due to the strong electron withdrawing effect of two fluorine atoms connected with cyclobutyl, the intermolecular Van der Waals' force is weakened, and due to the flexible adjustment of n-caprylic acid linear alkyl, the pour point of the refrigerating machine oil composition is as low as-50 DEG C or below, so that the refrigerating machine oil composition still has excellent flowability at an ultralow temperature, and the refrigerating machine oil composition can be widely applied to refrigerating machines. Therefore, the lubricating oil has the advantages of excellent viscosity-temperature performance, excellent lubricating performance and low pour point.

The invention discloses a solid superacid catalyst as well as a preparation method and application thereof, and belongs to the technical field of catalyst preparation. The catalyst comprises a mesoporous carrier, sulfate radicals combined on the mesoporous carrier and rare earth ions doped on the mesoporous carrier, wherein the mesoporous carrier is formed by compounding ZrO2 and Al2O3; the rare earth ions are Yb < 3 + > and Ce < 3 + >. The solid superacid catalyst provided by the invention has the advantages that the active components are uniformly dispersed, the catalytic activity is high, the conversion rate of ethyl n-caprylate in a capryloyl hydroximic acid preparation process can be improved, and meanwhile, the cycle service life of the catalyst is prolonged.

The invention provides a preparation method of an oxime ester compound, and belongs to the technical field of photoresist. The preparation method of the oxime ester compound comprises the following steps: carrying out Friedel-Crafts reaction on a compound shown in a formula I and a compound shown in a formula II to obtain a compound shown in a formula III; performing oximation reaction on the compound in the formula III to obtain a compound in a formula IV; performing esterification reaction on the compound in formula IV to obtain a compound in formula V; therefore, 2-[(E)-acetoxyl nitrogen subunit]-1-[4-(phenyl sulfenyl) phenyl] octyl-1-ketone is prepared through the reaction of diphenyl sulfide and n-caprylic acid, the reaction of 1-[4-(phenyl sulfenyl) phenyl]-1-octanone and sodium nitrite or alkyl nitrite, and the reaction of (2E)-2-(isonitroso)-1-[4-(phenyl sulfenyl) phenyl] octane-1-ketone and an acetylation reagent. The production cost for preparing the oxime ester compound is reduced, and the yield and the purity of the oxime ester compound are improved.

The invention belongs to the technical field of refrigerating machine oil, and particularly relates to refrigerating machine oil for an HFOs refrigerant, a working fluid composition and application. The polyol ester is prepared from the following raw materials: polyol, first carboxylic acid and second carboxylic acid; the polyol comprises at least one of dipentaerythritol, pentaerythritol and trimethylolpropane, the first carboxylic acid comprises caprylic capric acid, and the second carboxylic acid comprises at least one of isononanoic acid, isocaprylic acid and adipic acid. After isocaprylic acid in the synthetic ester raw material is replaced by caprylic-capric acid, the strength of an oil film formed after the caprylic-capric acid is mixed with a refrigerant is greatly enhanced, and the lubricating effect is remarkably improved; the subsequent research finds that compared with independent n-caprylic acid or n-capric acid serving as a raw material of dipentaerythritol ester, pentaerythritol ester and trihydroxy propane ester, the strength of a corresponding synthetic ester oil film is higher, the lubricating effect is better when the caprylic capric acid serves as refrigerating machine oil, and the minimum four-ball wear scar diameter can reach 0.653 mm.