43 results about "Ventilator-associated pneumonia" patented technology

Apparatus for indicating the angular position of a patient support surface such as a mattress relative to the direction of gravity is disclosed. An angle sensor mounted to a frame associates with the patient support surface to create an output responsive to changes in position relative to gravity. Circuitry transmits an output signal to activate a display of the angular position of the patient support, thereby indicating whether the angular position is within a predetermined range. Preferably, the apparatus has a circuit for activating an indicator light, which more preferably mounted above the patient support surface. In certain preferred embodiments the apparatus that comprises the light is connected to the headboard, or the like. It is preferred that the apparatus has a memory device for storing positional information comprising at least a predetermined angular measurement, and more specifically that there is a device for storing information pertaining to the length of time said patient support has been set to an angular position is within a predetermined range.

Disclosed herein is a novel tube-in-tube endotracheal tube apparatus that allows for replacement or cleaning of an inner (first) tube without having to re-intubate the patient. The novel endotracheal tube apparatus enables the application of continuous suction or intermittent suction. The endotracheal device also serves to decrease the incidence of ventilator-associated pneumonia (VAP).

Ventilator associated pneumonia (VAP) may be prevented in a patient, or its occurrence reduced in a population of patients, by using an anti-VAP device or an anti-VAP material. By reducing the problem of bacterial-containing secretions that otherwise build up in the airway of the intubated patient, VAP can be prevented from occurring in intubated patients, such as patients intubated with an endotracheal tube (ETT) or a nasogastric tube.

The present invention provides carbapenems to treat or prevent pulmonary infections, particularly in patients with cystic fibrosis, pneumonia, ventilator associated pneumonia, bronchitis or bronchiectstasis, pharmaceutical compositions of these carbapenems and methods of administering these carbapenems to treat or prevent pulmonary infections.

An airway ventilation device for insertion in an elongate body cavity is provided. The airway ventilation device includes an endotracheal tube and an inflation cuff. The inflation cuff is toroidal in shape and includes one or more recessed attachment zones which allow for movement of the endotracheal tube without breaking the seal between the inflation cuff and the elongate body cavity.

The invention relates to the technical field of medical apparatus. The generation of ventilator-associated pneumonia is the result of the inspiration of secretion with pathogen, wherein the bacterialcontamination in a ventilator air tube is also a principal element for causing the ventilator-associated pneumonia. The invention aims to provide a manual tracheotomy tube with broad spectrum of antimicrobial activity and controllable slow-release medicaments, comprising a flexible tube body and a tampon system attached to the outside of the tube body, wherein the inner surface and the outer surface of the tracheotomy tube are combined with macromolecular polymer antimicrobial coatings in which medicaments with pharmacologic effect are loaded. The invention not only achieves the efficacy of providing air paths for a traditional tracheotomy tube and keeping the respiratory tract smooth, but also has excellent bacteriostatic effect and the slow release effect of the controllable medicaments,thereby providing a wide application prospect for clinical application of the manual tracheotomy tube.

The embodiment of the invention discloses a ventilator-associated pneumonia decision-making assistance method, device, equipment and medium. The method comprises the steps of receiving patient sign data sent by a vital sign monitoring device; obtaining patient test data through a hospital management system; according to the patient sign data, the patient test data, and a pre-trained obtained diagnostic treatment model, generating auxiliary diagnostic information, wherein the diagnostic treatment model is obtained based on corpus training of ventilator-associated pneumonia. The ventilator-associated pneumonia decision-making assistance method can provide clinical medical personnel with auxiliary decision-making information of 'prevention to treatment' of the ventilator-associated pneumonia,timely and effectively diagnose and treat the ventilator-associated pneumonia for patients, improve the diagnostic efficiency of the ventilator-associated pneumonia, effectively reduce medical errors, improve the quality of medical care, and save a lot of cost for a hospital.

The invention relates to methods for treating bacterial infection of the respiratory tract, including pneumonias, such as ventilator-associated pneumonia, and to methods for treating ventilator-associated tracheobronchitis, comprising administering an effective amount of a salt formulation as an aerosol to the respiratory tract of an individual in need thereof. The formulations can also be used to reduce transmission of pathogen which can infect the respiratory tract, cause pneumonia or cause ventilator-associated tracheobronchitis.

The invention discloses novel device and method for monitoring pressure of an artificial airway gasbag. The novel device for monitoring pressure of the artificial airway gasbag comprises an application terminal and a PC control terminal. The application terminal is used for performing real-time monitoring on pressure of an artificial airway gasbag of a patient with intubation as well as carrying out automatic control, and then, sending out acousto-optic alarm when the pressure exceeds normal range; and the application terminal comprises a gasbag interface, an air pump, a pressure sensor, a solenoid valve, an AD chip, a single chip, a liquid crystal display, a key circuit, an acousto-optic alarm, a power module, an external power connector, a power switch, a 9V battery and an RS232 serial port. The PC control terminal realizes intelligent management on gasbag pressure data on basis of a personal terminal. The novel device and method for monitoring pressure of the artificial airway gasbag overcome the disadvantages of monitoring methods of existing artificial airway gasbag pressure gauges, and effectively achieve intelligent management on gasbag pressure, thereby reducing incidence of ventilator-associated pneumonia and decreasing damage on airway mucosa; and thus, the novel device and method are of great significance to mechanical ventilation treatment on patients.

Described herein are devices and methods for preventing ventilator associated pneumonia following intubating a patient with an endotracheal tube (ETT). Secretions that accumulate in the trachea above the ETT cuff are wicked out of the patient.

The invention provides a Peptocin antibacterial peptide separated from heterometrus spinifer and obtained through a chemical synthesis method. The antibacterial peptide has a remarkable antibacterial effect on clinically-separated multi-drug resistant acinetobacter baumannii, and can be used for efficiently inhibiting the growth of the drug resistant acinetobacter baumannii; and meanwhile, human red blood cell toxicity tests also show that the antibacterial peptide is small in toxicity and can be applied to the preparation of drugs for treating or preventing diseases caused by the drug resistant acinetobacter baumannii and particularly to the preparation of drugs for treating serious infectious diseases such as ventilator-associated pneumonia, septicemia, meningitis, otitis media, skin soft-tissue infection, urinary system infection, central nervous system infection and the like caused by the drug resistant acinetobacter baumannii. The antibacterial peptide provided by the invention is remarkable in inhibiting effect on gram bacteria, unique in antibacterial mechanism and low in toxicity, and can also be applied to the preparation of drugs for treating or preventing diseases caused by micrococcus luteus, salmonella and other gram bacteria.

The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.

An intubation tube oral appliance system for providing a semi-customized support for an intubation tube that protects the intubation tube and facilitates the delivery of oral hygiene materials to reduce the incidences of ventilator associated pneumonia (VAP). The intubation tube oral appliance system generally includes a tube support, a first tray extending from the tube support and a second tray extending from the tube support. The tube support is formed to receive an intubation tube and a strap or securing member secures the intubation tube to the tube support. The first tray and the second tray include a thermoplastic layer that is formed to the ventilation patient's teeth. An antibacterial solution and/or fluoride solution is placed within the first tray and second tray prior to insertion into the ventilation patient's mouth to reduce dental plaque and VAP.

Compounds of Formula I: wherein: X1, and X2 are each independently either O- or S-; X3 and X4 are each independently either -H or -OH, with the proviso that X3 and X4 are not simultaneously -H; R1 is selected from the group consisting of O, imido, methylene and dihalomethylene; R2 is selected from the group consisting of H, halo, alkyl, substituted alkyl, alkoxyl, nitro and azido; R3 is selected from the group consisting of H, alkyl, acyl, aryl, and arylalkyl; and R4 is selected from the group consisting of -OR', -SR', -NR', and -NR'R'', wherein R' and R'' are independently selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, alkoxyl, and aryloxyl, with the proviso that R' is absent when R4 is double bonded from an oxygen or sulfur atom to the carbon at the 4-position of the pyrimidine ring, are used in methods of hydrating lung mucus secretions and treating lung disorders such as cystic fibrosis, ventilator-associated pneumonia, chronic bronchitis, chronic obstructive pulmonary disorder and primary ciliary dyskinesia. Pharmaceutical compositions containing compounds of Formula I, and novel compounds of Formula I are also described.

The invention discloses an apparatus for detecting and analyzing oral inner ambient of a patient via an oral tracheal cannula; the apparatus comprises a computer, a data processor, a scanning device, a travel cart and a saliva collection device; the data processor and the scanning device are connected with the computer, and the computer, the data processor and the saliva collection device are arranged on the travel cart; during detection, medical staff holds the scanning device by hand to scan the patient's lips, gums, oral mucosae, tongue and teeth, a saliva collection bottle is used to collect the patient's saliva, the data processor analyzes scanning results and saliva results, and the medical staff provides nursing for the patient according to obtained assessing results, nursing frequency and nursing time. The apparatus allows the oral ambient to be accurately assessed and analyzed so as to formulate nursing frequency and nursing time and to assist clinical nurses in formulating a reasonable oral care plan according to the oral inner ambient of the patient, thereby decreasing chances for the patient to suffer VAP (ventilator-associated pneumonia).

The present invention is synergistic antibiotic compositions having pH adjusted profiles for manufacturing combination, and administration, particularly for patients at risk or suffering from ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic compositions containing fosfomycin and aminoglycosides having individually predetermined and selected pH ranges are manufactured and stored for in combination prior to aerosolization, preferably with a specially designed in-line nebulizer attached to a ventilator.

The invention relates to a device capable of simultaneously sucking secretion in a trachea and a trachea cannula and rinsing and cleaning the inner wall of the trachea cannula, which is characterized in that: the pipe wall of a suction catheter (1) is provided with at least three small pipes (2) which are parallel and equidistant; one end of each small pipe is opened on the pipe wall (3) of the suction catheter and has a distance of between 20 and 50 mm from a remote opening of the suction catheter, while the other ends of the small pipes are integrated into a pipeline (4) at the near end of the suction catheter, and the opening of the pipeline (4) can be connected with an injector; and the surface of the suction catheter is provided with a granulated scale (5). By rinsing and cleaning the inner wall of the trachea cannula at fixed positions, colonized bacteria and sputum crusts are prevented from appearing on the inner wall of the trachea cannula, the occurrence of ventilator associated pneumonia is reduced and the curative effect of mechanical ventilation is improved.

A composition and method for prevention and treatment of otitis media and ventilator-associated pneumonia are described. The composition is made with GTase inhibitory polyphenol and polyhydric alcohol carrier. The composition is topical for intra-oral and otic use.

The invention discloses a multifunctional pressure monitoring system. The multifunctional pressure monitoring system comprises a mode recognition module, a mode switching module, a pressure monitoringmodule and a display module, wherein the mode recognition module is used for recognizing the type of a tracheal plug currently connected to the system; the mode switching module is used for switchingcurrent working modes according to the type of the tracheal plug, and the working modes include, but are not limited to, a blood pressure monitoring mode and an airbag pressure monitoring mode; the pressure monitoring module is used for pressure monitoring in different working modes; and the display module is used for displaying monitoring results of the pressure monitoring module. The inventionalso discloses a multifunctional pressure monitoring method. By use of the method, the blood pressure of a patient can be measured, the airbag pressure of the tracheal intubation patient can be monitored, and the occurrence of ventilator associated pneumonia (VAP) can be reduced.