The invention relates to an administration
package (1A, 1) for a pharmaceutical product (2) and to a device and to a method for producing and filling such an administration
package (1A, 1). A predetermined breaking zone (10, 9) is produced by
thermoforming for opening the application
package (1A, 1) by breaking the breaking zone (10, 9). For this purpose, the device comprises a moulding tool (102A, 102) having a
moulding device for forming the predetermined
fracture zone (10, 9). Alternatively or in addition, the predetermined breaking zone (10, 9) may form a reduced cross-section or
nozzle (19) of the application channel (7A, 7) of the application package (1A, 1).