Phellodendron bark disperse tablet and its preparation method

A technology of dispersible tablets and Cortex Phellodendron, which is applied in the field of Cortex Phellodendron dispersible tablets and its preparation, can solve the problems of large dosage and slow effect, and achieve the effect of small dosage, fast absorption and rapid onset of effect

Inactive Publication Date: 2007-10-10
唐德江
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Phellodendron phellodendron pharmaceutical preparations in the prior art are capsules, but there are defects such as large dosage and slow effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Take the raw materials according to the following proportioning (by weight):

[0079] Phellodendron 100 Excipients (microcrystalline cellulose: sodium carboxymethyl starch = 1:1) 10

[0080] The production method is as follows:

[0081] Take Cortex Phellodendri, add water to decoct four times, add 10 times the amount of water for the first time, add 8 times the amount of water for the second, third, and fourth times, each time for 30 minutes, combine the decoctions, filter, and concentrate the filtrate to about half the amount under reduced pressure. At 80°C, add 2% calcium hydroxide of Cortex Phellodendri, stir well, keep warm for 10 minutes, filter while hot, and concentrate the filtrate under reduced pressure to a clear paste with a relative density of about 1.10 (60°C), dry it, collect the dry powder, add The auxiliary materials are mixed evenly, granulated with 75% ethanol solution containing povidone K30 in an appropriate amount, dried at below 60°C, and compress...

Embodiment 2

[0083] Take the raw materials according to the following proportioning (by weight):

[0084] Phellodendron 100 Excipients (microcrystalline cellulose: hydroxypropyl cellulose = 1:1) 10

[0085] The production method is as follows:

[0086] Take Cortex Phellodendri, add water to decoct four times, add 10 times the amount of water for the first time, add 8 times the amount of water for the second, third, and fourth times, each time for 30 minutes, combine the decoctions, filter, and concentrate the filtrate to about half the amount under reduced pressure. At 80°C, add 2% calcium hydroxide of Cortex Phellodendri, stir well, keep warm for 10 minutes, filter while hot, and concentrate the filtrate under reduced pressure into a clear paste with a relative density of about 1.10 (60°C), dry it, collect the dry powder, add The auxiliary materials are mixed evenly, granulated with 75% ethanol solution containing povidone K30 in an appropriate amount, dried at below 60°C, and compressed...

Embodiment 3

[0088] Take the raw materials according to the following proportioning (by weight):

[0089] Phellodendron 100 Excipients (microcrystalline cellulose: sodium carboxymethyl starch: hydroxypropyl cellulose = 1:1:1) 10

[0090] The production method is as follows:

[0091] Take Cortex Phellodendri, add water to decoct four times, add 10 times the amount of water for the first time, add 8 times the amount of water for the second, third, and fourth times, each time for 30 minutes, combine the decoctions, filter, and concentrate the filtrate to about half the amount under reduced pressure. At 80°C, add 2% calcium hydroxide of Cortex Phellodendri, stir well, keep warm for 10 minutes, filter while hot, and concentrate the filtrate under reduced pressure into a clear paste with a relative density of about 1.10 (60°C), dry it, collect the dry powder, add The auxiliary materials are mixed evenly, granulated with 75% ethanol solution containing povidone K30 in an appropriate amount, drie...

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PUM

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Abstract

A dispersing tablet of phellodendron bark is prepared from phellodendron bark and the medicinal auxiliary including microcrystalline cellulose, and carboxymethyl starch sodium and / or hydroxypropyl cellulose. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating diseases such as damp-heat diarrhea, jaundice, leukorrhea, hot stranguria, beriberi, flaccidity, night sweats, spermatorrhea, sores, swelling and pain, damp-heat pruritus and the like. Specifically, it is a Chinese patent medicine prepared from Chinese herbal medicines, and the invention also relates to a preparation method of the medicine. technical background [0002] There are differences between gastrointestinal diseases and urinary system diseases, but traditional Chinese medicine believes that damp-heat pathogenicity is an important aspect of its occurrence, and treating different diseases with the same treatment is an important principle of TCM syndrome differentiation. [0003] Phellodendron Phellodendron has the functions of clearing away heat and dampness, purging fire and eliminating steam, detoxifying and treating sores, etc. It is used to treat diseases caused by TCM syndrome differentiation...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K9/20A61P1/12A61P13/00A61P15/00A61P17/00A61P43/00A61K129/00
Inventor 唐德江陈犁
Owner 唐德江
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