Refining method for caoshanhu by menbrane technology separation

Abstract

The present invention relates to the membrane separating extraction process of sacandra glabra as one kind of Chinese medicinal materials. Sacandra glabra is decocted and membrane separated to reach high effective component yield and low extraction power consumption. Sacandra glabra decoction is ultrafiltered with organic membrane of polysulfone, acetate cellulose, polyacrylonitrile or polyimide with intercepting molecular weight 1000-20000, so as to eliminating tannin, protein, starch and resin, with the permeated liquid being decompression concentrated via conventional process. The said process is simple, has no organic solvent consumption and low cost, and is suitable for automatic production.

Description

technical field [0001] The invention relates to a membrane separation technology extraction method of the Chinese medicinal material Coralia praecox, that is, for the water decoction of Coral praecox, the membrane separation process is used to realize the separation and extraction of Coral praecox with high yield and low energy consumption. Background technique [0002] Grass coral [Sarcandrm glabra (Thunb.) Nakai], also known as sarcandrm glabra (Thunb.) Nakai, is a plant of the genus Sarcandrm glabra (Thunb.) Nakai. The chemical composition of Grass Coral shows that the whole plant contains flavonoid glycosides, isoxazinidine, fumaric acid, succinic acid, tannic acid, and trace element manganese. In addition to the above active ingredients, there are also a large amount of tannin Macromolecular substances such as protein, starch, and resin, as well as impurities such as many particles, subparticles, and flocs. The existing extraction and separation technology of Herba Cor...

AI Technical Summary

Problems solved by technology

The existing extraction and separation technology of Herba Cortex mainly adopts the method of water extraction and alcohol precipitation, such as under the preparation method of "Compound Herb Coral Buccal Tablets" in the 2000 edition of "Chinese Pharmacopoeia"; In the 9th issue of the volume "Development and Clinical Application of Mouth Ulcer Yitie Ning Film", the extraction and separation technology of the grass coral is mainly to use different concentrations of ethanol for percolation extraction; the publication number is CN1528389A "Caoshan coral powder injection and its preparation method" patent In the literature, the extraction and separation technology of grass coral mainly adopts water extraction and alcohol precipitation, and then ultrafiltration of the alcohol solution; the above methods are not only difficult to remove impurities, but also easily lose active ingredients and even waste a large amount of organic solvents. At the same time, the extraction yield and purity Therefore, it is particularly urgent to find an extraction method with simple operation process, low energy consumption and high purity.