Method of detecting cancer cells by utilizing biomagnetic piezoelectric sensing array
A technology of piezoelectric sensing and magnetic induction, applied in the direction of measuring devices, instruments, scientific instruments, etc., to achieve the effect of simplifying the analysis process
Inactive Publication Date: 2008-11-19
SHANGHAI JIAOTONG UNIV
View PDF2 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
However, so far, there is no report on a nanobioelectronic detection method that can accurately and rapidly detect cell properties in complex systems without the need for an immune reaction on the sensor surface.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0017] The technical solution of the present invention will be further described below in conjunction with the accompanying drawings.
[0018] The biological magnetic induction piezoelectric sensing array adopted by the method of the present invention is composed of several identical working units, and the structure of each working unit is as follows: figure 1 As shown, it mainly includes the signal acquisition system 2, the main body of the working unit composed of the upper platform 11 and the lower platform 13, the micro-magnetic inductor 4, the micro-piezoelectric quartz resonator 6, the elastic sealing ring and the magnetic induction signal controller 14, etc. The upper platform 11 and the lower platform 13 made of polymer materials are used to synthesize the main body of the piezoelectric sensing working unit, and several micropositioners 10 are used for positioning and fixing around the upper and lower sides. The center of the upper platform 11 is a microcavity 8, and t...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
| Property | Measurement | Unit |
|---|---|---|
| size | aaaaa | aaaaa |
| diameter | aaaaa | aaaaa |
Login to View More
Abstract
This invention relates to method of using organism magnetic induction piezoelectricity sensor array detecting cancer cell. Specificity protein antibody magnetic micro ball comparing to tested cancer cell antigen and antibody attached on the ball surface is added into microreactor to make goal cell immune reacted to the magnetic micro ball. Anti body magnetic micro ball-antigen cancer cell organism generated is added into micro cavity that consisted by micro magnetic sensor, micropressure electrical quartz and other components. Organism assembly can quickly contact the quartz up surface to change its resonance frequency characteristic under action of micro magnetic inductor. Resonance signal of organism weight and quantity and the characteristic are changed into digital information. Immune nm magnetic microball technique and magnetic induction pressure electrical sensor array are intergrated to detect cell characteristic, it can detect few cancer cell in complex system of multiple kinds of cells, and it has high detecting sensitivity.
Description
technical field [0001] The invention relates to a biological magnetic induction piezoelectric sensor array for detecting cancer cells, which uses quartz crystal piezoelectric microsensor arrays, magnetic sensors and other components, and integrates a nanometer immunomagnetic microsphere for early diagnosis of malignant tumors. The bioelectronic detection microsystem uses immune nanomagnetic microspheres to capture the target cells in the sample to be tested, and converts the quality and quantity of the biological assembly to be tested into corresponding electronic information through the biomagnetic induction piezoelectric sensor array. Background technique [0002] Generally speaking, the methods for the diagnosis of lung cancer mainly include pathology, imaging, immunology, and molecular biology. The samples tested include sputum, mass, pleural effusion and blood. As far as the current imaging detection level of hospitals in our country is concerned, it is generally belie...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/574G01N33/546
Inventor 惠春徐爱兰
Owner SHANGHAI JIAOTONG UNIV