Use of steroidal compound and total steroidal extract for preparing anti-depression drug

A compound, total sterol technology, applied in the field of natural medicinal chemistry, can solve problems affecting the quality of life of patients, adverse reactions, toxic and side effects, etc.
CN100441191CInactive Publication Date: 2008-12-10BIOPHARML TECH SHANGHAI +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BIOPHARML TECH SHANGHAI
Publication Date
2008-12-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses the application of a sterol compound and a total sterol extract in preparing antidepressant drugs. The sterol compounds in the present invention mainly include sitosterol, stigmasterol, campesterol, brassicasterol, sterol glycosides, sterol esters and acylated sterol glycosides extracted from plants or traditional Chinese medicines. Animal experiments have shown that the above substances have antidepressant effects on mice.
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Description

Technical field:

[0001] The invention belongs to the technical field of natural medicinal chemistry. It specifically relates to the application of sterol compounds and total sterol extracts in the preparation of antidepressant drugs. Background technique:

[0002] Sterol compounds, especially sterol compounds in plants, mainly include sitosterol, stigmasterol, campesterol, brassicasterol, sterol glycosides, sterol esters and acylated sterol glycosides. Many plants contain sterol compounds, which mainly exist in the form of mixtures in plants.

[0003] There are also a lot of reports about the biological activity of sterols. For example, sterol glycosides have complement activation and anti-inflammatory activities; mixtures of sterol glycosides including β-sitosterol glucoside and other β-sitosterol glycosides have immunomodulatory effects; Exzema, psoriasis, asthma and tumors all play a role. Sterols lower cholesterol. However, the effects of sterol components on the ce...

Claims

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