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Producer of high-flux continuous homogeneous emulsion drop

A preparation device and high-throughput technology, applied in chemical instruments and methods, dissolution, mixers, etc., can solve the problems of continuous production difficulties, large power, particle size distribution, etc., and achieve the benefits of biological material activity and equipment The effect of small investment and low speed requirement

Inactive Publication Date: 2009-03-18
INST OF PROCESS ENG CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the device relies on self-priming to bring one phase into the channel and disperse it in the other phase, it requires relatively large power, and it is difficult to achieve continuous production
At the same time, the milk droplets that have been generated may be sucked into the channel again, and finally have a certain impact on the particle size distribution

Method used

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  • Producer of high-flux continuous homogeneous emulsion drop
  • Producer of high-flux continuous homogeneous emulsion drop
  • Producer of high-flux continuous homogeneous emulsion drop

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1. High-throughput continuous uniform emulsion droplet preparation device prepares polylactic acid microspheres with uniform particle size (rotating speed 400rpm)

[0027] Pour 800mL of dichloromethane solution (oil phase) dissolved with 5g of polylactic acid (molecular weight: 100,000) into a 1000mL dispersed phase storage tank, and pump it into the device continuously, controlling the pressure at 1.2bar. 3200mL of 1.0wt% polyvinyl alcohol (PVA) deionized aqueous solution (water phase) was poured into the container continuously through the feed port (11). use figure 1 The shown high-throughput continuous uniform emulsion droplet preparation device (the outlet hole diameter is 1mm) prepares oil / water emulsion. The rotation speed of the belt runner is 400rpm, and the prepared emulsion is continuously output from the outlet (12). Then, the above obtained emulsion was stirred with a magnetic mechanical stirrer at 150 rpm for 5 hours to ensure complete volatili...

Embodiment 2

[0031] Embodiment 2. High-throughput continuous uniform emulsion droplet preparation device prepares polylactic acid microspheres with uniform particle size (rotating speed 300rpm)

[0032] Pour 800mL of dichloromethane solution (oil phase) dissolved with 5g of polylactic acid (molecular weight: 100,000) into a 1000mL dispersed phase storage tank, and pump it into the device continuously, controlling the pressure at 1.2bar. 3200mL of 1.0wt% polyvinyl alcohol (PVA) deionized aqueous solution (water phase) was poured into the container continuously through the feed port (11). use figure 1The shown high-throughput continuous uniform emulsion droplet preparation device (the outlet hole diameter is 1mm) prepares oil / water emulsion. The rotation speed of the belt runner is 300rpm, and the prepared emulsion is continuously output from the outlet (12). Then, the above obtained emulsion was stirred with a magnetic mechanical stirrer at 150 rpm for 5 hours to ensure complete volatiliz...

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PUM

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Abstract

The invention is concerned with continuous and even milk drop product equipment with high flux. Under the airtight and high press condition, the stuff enters into the top of hollow cylinder and comes out form the lower part of side wall, and the bottom connects with the cylinder and both of them is settled. The sleeve outside of the hollow cylinder and connecting with turning wheel and the turning canister outside of the cylinder and connecting with the bottom of sleeve move together with the turning wheel, and the liquid is thrown from the hole on the side wall of turning canister to get the latex. This continuously disperses one phase into another phase with low speed and high flux to produce milk drop with even diameter. It is fit for keeping the active of bio-matter, such as protein, and is easy to apply to industry with small and even shearing stress for solution, low investment, and continuous operation, low requirement with the speed of motor and low power.

Description

technical field [0001] The invention relates to an emulsion preparation device in the fields of medicine, biochemical industry, food and the like, in particular to a high-throughput continuous uniform emulsion drop preparation device. technical background [0002] With the continuous improvement of human living standards, people's demand for emulsions is becoming more and more extensive. For example: the use of emulsions in the food industry can reduce the intake of fat while ensuring the taste; in the cosmetics industry, people use emulsions , to minimize the loss of volatile and oxidizable substances in spices during storage. However, the traditional emulsion preparation methods (mechanical stirring method, homogeneous emulsification method, etc.) all have a common problem - excessive local shear force leads to uneven particle size of the prepared emulsion, so the stability of the emulsion is poor and the repeatability is not good. Especially when it is necessary to prepa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01F5/00B01F3/08
Inventor 马光辉宋薇苏志国卫强
Owner INST OF PROCESS ENG CHINESE ACAD OF SCI