Material for surgical suture

Abstract

The invention is a new material for surgical suturing, which is a new material processed by copolymerization or blending of biodegradable polylactic acid aliphatic polyester and polyamino acid materials. The selected degradable polymer is completely absorbed by the tissue within 60-180 days. The suture material maintains the highest level of tensile strength and nodular firmness both in vivo and in vitro, and at the same time, it has a stable and predictable absorption rate in conjunction with wound healing. It is simply hydrolyzed in the body and is not affected by enzymes and body fluids. It has good biocompatibility. The tissue response is low, which is very suitable for maintaining the complete anastomosis of sutures for a long time after surgery.

Description

technical field

[0001] The invention relates to a new suture material for wound suture or tissue ligation and tissue fixation in surgical operations, in particular a new material processed from biodegradable polylactic acid aliphatic polyester and polyamino acid material copolymerization or blend. Background technique

[0002] Medical suture is a special sterile thread for wound suture or tissue ligation and tissue fixation in surgical operations. At present, there are three kinds of medical sutures widely used: silk thread, catgut and aliphatic polyester absorbable suture. The production process of sheep catgut is backward, pollutes the environment, has poor absorbability, and is prone to allergies and antibody reactions. Aliphatic polyester absorbable sutures mainly include polyglycolic acid sutures, polyglycolic acid and polylactic acid copolymer sutures, polydioxanone (PDS) sutures, glycolide and trimethylene carbonate Sutures, etc., have the advantages of: because the...