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Traditional Chinese medicinal composition for treating protrusion of the intervertebral disc and preparation method and traditional Chinese medicine preparation

A technology for lumbar intervertebral disc herniation and traditional Chinese medicine preparation, which is applied in the field of preparation of traditional Chinese medicine compositions to achieve the effects of reducing inflammatory mediators and local immune responses, promoting regeneration and eliminating pain.

Inactive Publication Date: 2009-09-23
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are currently no effective therapeutic drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Weigh 15g of Zedoary Curcuma, crush it, add water, put it into a volatile oil extractor to extract, and carry out β-cyclodextrin inclusion inclusion of the obtained volatile oil. During inclusion, the weight ratio of volatile oil, β-cyclodextrin and water is 1:4:60 Add water to extract zedoary dregs, 30g astragalus, 15g epimedium, 15g coicis and 15g geranium, concentrate the water extract, add ethanol or chitosan to purify, filter and concentrate to obtain concentrated solution A; weigh the ground beetle 5g, pulverized, added water and homogenized to obtain solution B; combined solution B and concentrated solution A, dried in vacuum, compounded the obtained powder with β-cyclodextrin inclusion compound of zedoary volatile oil, and mixed well.

Embodiment 2

[0023] Weigh 20g of Zedoary Curcuma, crush it, add water, put it into a volatile oil extractor to extract, and carry out β-cyclodextrin inclusion inclusion of the obtained volatile oil. During inclusion, the weight ratio of volatile oil, β-cyclodextrin and water is 1:10:100 Add water to extract zedoary dregs, 40g astragalus, 20g epimedium, 20g coix seed and 20g geranium, add ethanol or chitosan to the water extract after concentration, filter and concentrate to obtain concentrated solution A; 10g, pulverized, added water and homogenized to obtain solution B; combined solution B and concentrated solution A, dried in vacuum, compounded the obtained powder with β-cyclodextrin inclusion complex of zedoary volatile oil, and mixed well.

Embodiment 3

[0025] Weigh 18g of Zedoary Curcuma, crush it, add water, put it into a volatile oil extractor to extract, and carry out β-cyclodextrin inclusion inclusion of the obtained volatile oil. During inclusion, the weight ratio of volatile oil, β-cyclodextrin and water is 3:4:100 Add water to extract zedoary dregs, 45g astragalus, 18g epimedium, 16g coix seed and 16g geranium, add ethanol or chitosan to the water extract after concentration, filter and concentrate to obtain concentrated solution A; weigh the ground beetle 8g, pulverized, added water and homogenized to obtain solution B; combined solution B and concentrated solution A, dried in vacuum, compounded the obtained powder with β-cyclodextrin inclusion compound of zedoary volatile oil, and mixed well.

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PUM

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Abstract

The utility model relates to a Chinese medicinal composition for treating lumbar intervertebral disc protrusion comprising raw materials in weight percentage as follows: astragalus root 30-45%, epimeddium 15-20%, zedoary 15-20%, coix seed 15-20%, herb of common heron's bill 15-20%, ground beetle 5-10%. The invention also relates to a Chinese medicinal formulation for treating lumbar intervertebral disc protrusion comprising 70-90% of the above Chinese medicinal composition for treating the lumbar intervertebral disc protrusion and 10-30% of medicinal adjuvant. The provided Chinese medicinal composition and Chinese medicinal formulation are applicable to lumbar intervertebral disc protrusion, cervical spondylosis, scapulohumeral periarthritis, gonarthritis, spinal canal stenosis and sciatica. In addition, the invention also relates to a method for preparing the above Chinese medicinal composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating lumbar intervertebral disc herniation and a traditional Chinese medicine preparation thereof; the invention also relates to a preparation method of the traditional Chinese medicine composition for treating lumbar intervertebral disc herniation. Background technique [0002] Lumbar and leg pain is the most common pain syndrome in people, which often brings adverse effects on people's production, work, study and life, and also brings heavy burdens to families and society. [0003] Lumbar disc herniation is one of the common lumbar diseases clinically, and the incidence rate in the population is about 15.2%. Its onset is mainly due to the degenerative changes of the lumbar intervertebral disc tissue. Under the action of various external forces, the fibrous annulus of the intervertebral disc ruptures, and the nucleus pulposus tissue protrudes from the rupture, which stimulates...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/906A61K36/899A61K36/481A61K36/296A61K36/185A61K35/64A61K9/48A61K9/22A61K9/20A61K9/16A61K9/107A61K9/08A61P19/08
Inventor 施杞王拥军张宁刘梅周泉李晨光周重建
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE