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Method for preparing Yueshu dripping pills to treat dysmenorrhea

A technology for Yueshu dripping pills and dysmenorrhea, which is applied to medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc., can solve the problems of unsatisfactory pain relief, complicated production process, inconvenient taking, etc., and improve bioavailability. , the production process is simple, the effect is convenient to take

Active Publication Date: 2010-06-16
津药达仁堂集团股份有限公司第六中药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the side effects of these Chinese patent medicines are relatively small, because they are mostly capsules or pills, they are often slow to take effect, inconvenient to take, and the production process is very complicated and costly. Dropping pills for treating dysmenorrhea and its new technology have been reported
In addition, the above-mentioned Chinese patent medicines mainly play the role of promoting blood circulation, removing blood stasis and regulating menstruation, but the analgesic effect is not ideal.

Method used

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  • Method for preparing Yueshu dripping pills to treat dysmenorrhea
  • Method for preparing Yueshu dripping pills to treat dysmenorrhea
  • Method for preparing Yueshu dripping pills to treat dysmenorrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] (a) Add 10g angelica sinensis and 10g dried ginger to 50% ethanol which is 5 times its total weight, and extract by reflux once for 2 hours, then recover the ethanol from the extract and concentrate it to a relative density of 1.15-1.20 (80°C), After cooling, extract once with ethyl acetate in an amount equal to 1 times the total weight of the extract concentrate, recover the ethyl acetate from the extract and concentrate to obtain extract 1;

[0017] (b) 80g Yuan Hu was added to 50% ethanol which was 5 times its weight and refluxed for 1 time for 2 hours, then the extract was recovered to ethanol and concentrated to a relative density of 1.05-1.10 (80°C), and the extracted concentrate adjusting the pH value to 9, and extracting once with ethyl acetate in an amount equal to 1 times the total weight of the extract concentrate, recovering the ethyl acetate from the extract and concentrating it to obtain extract 2;

[0018] (c) Heat and melt the polyethylene glycol-6000 wh...

Embodiment 2

[0020] (a) 30g Angelica sinensis and 20g dried ginger are added to 70% ethanol which is 8 times the amount of its total weight and refluxed for 2 times, for the first time use 4 times the amount of ethanol to extract for 2 hours, and for the second time use 4 times the amount of ethanol Extract with ethanol for 1 hour, then combine the extracts, recover the ethanol and concentrate to a relative density of 1.15-1.20 (80°C), after cooling, extract twice with n-butanol which is 1.5 times the total weight of the extract concentrate, the first time is 1 times the amount, the second time is 0.5 times the amount, after the extracts are combined, n-butanol is recovered and concentrated to obtain extract 1;

[0021] (b) 50g Yuan Hu was added to 8 times of its weight in 70% ethanol for reflux extraction for 2 times, the first time was extracted with 4 times of ethanol for 2 hours, and the second time was extracted with 4 times of ethanol for 1 hour, Then the extracts are combined and th...

Embodiment 3

[0024] (a) 50g Angelica sinensis and 30g dried ginger are added to 85% ethanol which is 10 times the amount of its total weight and refluxed for 3 times, for the first time use 4 times the amount of ethanol to extract for 3 hours, and for the second time use 3 times the amount of ethanol Extract with ethanol for 2 hours, and extract with 3 times the amount of ethanol for 1 hour for the third time, then combine the extracts, recover the ethanol and concentrate to a relative density of 1.15-1.20 (80°C), cool and use to extract 2.0 times the total weight of the concentrated solution The amount of butanone was extracted 3 times, the first time was 1 times the amount, and the second and third times were 0.5 times the amount. After the extracts were combined, butanone was recovered and concentrated to obtain extract 1;

[0025] (b) 20g Yuan Hu was added to 85% ethanol which was 10 times its weight and refluxed for 3 times, the first time was extracted with 4 times the amount of ethan...

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Abstract

A medicine 'Yueshu dripping pill' for treating primary menalgia and its preparing process using polyethonediol as carrier are disclosed.

Description

technical field [0001] The invention relates to a method for preparing a traditional Chinese medicine drop pill for treating dysmenorrhea, in particular to a method for preparing Yueshu drop pill for treating primary dysmenorrhea or dysmenorrhea of ​​cold coagulation and blood stasis type according to TCM dialectics. Background technique [0002] Dysmenorrhea is a common disease in which women experience periodic lower abdominal pain during or before and after menstruation. Primary dysmenorrhea refers to those who have no obvious organic lesions in the reproductive organs found in gynecological examination. The disease mainly occurs in adolescent girls or young women who have not given birth 2-3 years after the beginning of menstruation. Most girls or young women who have not given birth have symptoms of dysmenorrhea. In severe cases, symptoms such as lower abdomen pain, waist pain, pale face, cold sweat, cold limbs, vomiting and diarrhea, or anal bulging have seriously affe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/9068A61P15/00A61P29/02
Inventor 佟永领高小芳苏文琴
Owner 津药达仁堂集团股份有限公司第六中药厂
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