Unlock instant, AI-driven research and patent intelligence for your innovation.

Method of synthesizing poly p-dioxycyclohexanone and reaction apparatus thereof

A technology of polydioxanone and p-dioxanone, which is applied in the field of preparation of polydioxanone, can solve problems such as difficulty in expanding production, difficulty in stirring, and harsh synthesis conditions, and achieves a solution to the problem of synthesis Harsh conditions, shortened water removal cycle, repeatable and stable effect

Active Publication Date: 2007-08-15
成都普利铭医用材料科技有限责任公司
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because in bulk polymerization, as the reaction proceeds, the viscosity of the product will continue to increase, resulting in very difficult stirring, so that only blocky polymerization products can be obtained at the end of the reaction, which not only brings great difficulties to further expand production , its industrial production has not been realized, and the cost of polydioxanone remains high due to the harsh synthesis conditions and the difficulty in post-processing of bulk products, which limits its application in general materials. application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method of synthesizing poly p-dioxycyclohexanone and reaction apparatus thereof
  • Method of synthesizing poly p-dioxycyclohexanone and reaction apparatus thereof
  • Method of synthesizing poly p-dioxycyclohexanone and reaction apparatus thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] As shown in Figure 1, the reaction device of this embodiment is composed of a reaction vessel 1, a water remover 4, a cooler 10, and a dryer 11. The water remover 4, a cooler 10, and a dryer 11 are sequentially installed above the reaction vessel 1. . The reaction vessel 1 is a single-necked flask with an inflatable mouth commonly used in laboratories, and a stirrer 2 is placed in it. The middle section of the water eliminator 4 is a cylinder with an open upper part, a small hole 5 is opened on the bottom surface, and a molecular sieve 6 is installed in the cylinder. A gas-liquid guide tube 7 matching the inner diameter of the connecting port of the reaction vessel 1 is located under the cylinder. A connecting port 8 matching the outer diameter of the connecting end of the cooler is extended from above, and there is a parallel air flow side pipe 9 on one side of the cylinder. The two ends of the side pipe 9 are respectively communicated with the gas-liquid guide tube 7 and ...

Embodiment 2

[0028] As shown in Figure 2, the reaction device of this embodiment is also composed of a reaction vessel 1, a water remover 4, a cooler 10, and a dryer 11. The water remover 4, a cooler 10, and a dryer 11 are sequentially installed above the reaction vessel 1. . The difference from Example 1 is that the reaction vessel 1 is a three-necked flask commonly used in laboratories, the middle bottle mouth is equipped with a stirrer 3, the water eliminator 4, the cooler 10, and the dryer 11 are sequentially installed above the mouth of one side of the bottle. The mouth of the bottle on the other side is used as an inflation port. Since the structure and connection relationship of the water eliminator 4, the cooler 10, and the dryer 11 are completely the same as those of the first embodiment, the description is omitted.

Embodiment 3

[0030] As shown in Figure 3, the reaction device of this embodiment is also composed of a reaction vessel 1, a water remover 4, a cooler 10, and a dryer 11. The water remover 4, a cooler 10, and a dryer 11 are sequentially installed above the reaction vessel 1. . The difference from Example 1 is that the reaction vessel 1 is a reactor, so the water remover 4 can be connected to it through a flange provided at the end of the gas-liquid guide tube 7; the cooler 10 is a tube cooler, which is connected to the water removal device. The device 4 is also connected by flanges. Since the structure of the water eliminator 4 is exactly the same as that of Embodiment 1, the description is omitted.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Intrinsic viscosityaaaaaaaaaa
Intrinsic viscosityaaaaaaaaaa
Intrinsic viscosityaaaaaaaaaa
Login to View More

Abstract

The invention discloses a method to synthesize poly-p-dioxide nadone, which comprises the following steps: allocating poly-p-dioxide nadone and tape water agent with volumetric ratio at 1 : 3-5 in reacting device with dehydrator; azeotropic refluxing 0.5-3 h; protecting with inert gas; stirring; dipping activator with mole ratio at 1 : 550-5000 against poly-p-dioxide at the same time; reacting under 60-100 deg.c at 0.5-48 h; getting depositing product; taking-up depositing product; drying; getting the final product. This invention also discloses a device fit for this method. The invention possesses short de-watering cycle and stable property, which can acquire small block, particulate or powdered poly-p-dioxide.

Description

Technical field [0001] The invention belongs to the technical field of preparation methods and devices for polydioxanone, and specifically relates to a simple and feasible way of removing water to achieve the anhydrous and oxygen-free effect required for the polymerization of dioxanone, and can The synthesis method and reaction device for controlling the final form of the synthesized poly(p-dioxanone). Background technique [0002] With the increase of people's awareness of environmental protection and the reduction of white pollution, it has become a consensus to develop and use biodegradable polymer materials. As a biodegradable polyester, aliphatic polyester has been favored by researchers at home and abroad due to its good mechanical properties and higher use temperature. It has developed in the fields of medical materials and general materials. [0003] As one of the aliphatic polyesters, poly(p-dioxanone), in addition to the above-mentioned advantages, has a unique ether bo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08G63/42C08G63/84C08G63/85
Inventor 王玉忠李以东曾建兵杨科珂汪秀丽陈思翀丁颂东周茜
Owner 成都普利铭医用材料科技有限责任公司