Buyang huanwu gantong medicine for preventing and curing cardiovascular or cerebrovascular disease and the agent and the method for preparing the same
A technology for cardiovascular and cerebrovascular diseases and pentaside ketones, which is applied in the field of traditional Chinese medicine, can solve the problems of unstable medicinal ingredients, unfavorable promotion and clinical application of Buyang Huanwu Decoction, and ambiguity, so as to achieve clear and controllable medicinal ingredients , Prevention and treatment of heart and brain ischemic diseases, definite curative effect
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Embodiment 1
[0035] Embodiment 1. The method for extracting buyanghuanpentaside ketone of the present invention:
[0036] Astragalus, Angelica, Radix Paeoniae Rubra, Chuanxiong, Safflower, Earthworm, and Peach Kernel all conform to the relevant provisions of the 2005 edition of the Chinese Pharmacopoeia. Take astragalus, angelica, chuanxiong, safflower, earthworm, and peach kernels, add 8 times the amount of water and decoct three times, 1.5 hours each time, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to (temperature 70°C, vacuum number -0.08Npa) Each 1ml is equivalent to 2g of the original medicinal material. Precipitate with 95% ethanol until the alcohol content reaches 80%, refrigerate and stand for 48 hours, filter, take the filtrate to concentrate and recover ethanol, refrigerate and stand for 24 hours, filter, and the filtrate passes through the polyamide column , wash with water to remove water-soluble impurities, elute with 70% ethanol, colle...
Embodiment 2
[0038] Embodiment 2. The extraction method of buyanghuanpentaglycone of the present invention:
[0039] Take astragalus, angelica, chuanxiong, safflower, earthworm, peach kernel and add 12 times of water to decoct three times, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to (temperature 70°C, vacuum number -0.08Npa) Each 1ml is equivalent to 2g of the original medicinal material. Precipitate with 95% ethanol until the alcohol content reaches 80%, refrigerate and stand for 48 hours, filter, take the filtrate to concentrate and recover ethanol, refrigerate and stand for 24 hours, filter, and the filtrate passes through the polyamide column , wash with water until there is no sugar reaction, elute with 80% ethanol, collect the eluate, filter, recover the ethanol, and concentrate until there is no alcohol smell, add 95% ethanol until the alcohol content reaches 90%, refrigerate for 24 hours, filter , recover ethanol, and...
Embodiment 3
[0041] Embodiment 3. The extraction method of buyanghuanpentaglycoside of the present invention:
[0042] Take astragalus, angelica, chuanxiong, safflower, earthworm, peach kernel and extract 8 times with alcohol three times, each time for 1.5 hours, combine the extracts, filter, and concentrate the filtrate under reduced pressure to (temperature 70°C, vacuum number -0.08Npa) Each 1ml is equivalent to 1g of the original medicinal material, add water to dilute to 1g of the original medicinal material per 4ml, refrigerate and stand for 48 hours, filter, the filtrate passes through a polyamide column, washes with water to remove water-soluble impurities, elutes with 80% ethanol, collects and washes Remove liquid, filter, recover ethanol, and concentrate until there is no alcohol smell, add 95% ethanol until the alcohol content reaches 90%, refrigerate for 24 hours, filter, recover ethanol, and concentrate under reduced pressure to dry powder.
[0043]Take Radix Paeoniae Rubra, ad...
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