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Active ingredient compound of Jianerqingjie solution and the control method

A technology of active ingredients and clearing solution, which is applied in the field of medicine, can solve problems such as unclear active substances, hidden dangers of drug safety, and influence on product efficacy, and achieve stable and controllable quality, increased safety and effectiveness, and better curative effect

Inactive Publication Date: 2007-09-26
SINOPHARM GRP ZHIJUN SHENZHEN PINGSHAN PHARMA CO LTD
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Problems solved by technology

Due to historical reasons, these products generally have unclear active substances and uncontrollable quality, which affects the efficacy of the product and even has hidden dangers in drug safety.

Method used

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Embodiment Construction

[0021] Below in conjunction with clinical situation the present invention is described in further detail:

[0022] Weigh the following traditional Chinese medicines by weight: honeysuckle 110g, chrysanthemum 100g, forsythia 65g, hawthorn 50g, bitter almond 50g, tangerine peel 2.5g. These Chinese medicines are made according to the following steps:

[0023] A: Separately distill honeysuckle, chrysanthemum, bitter almond and forsythia to extract aromatic water;

[0024] B: Heat and extract hawthorn and 80% ethanol twice, each time for two hours, filter, combine the filtrate, recover ethanol from the filtrate, concentrate it into an extract, add appropriate amount of water to dissolve;

[0025] C: The percolation method under the liquid extract and extract of dried tangerine peel (2000 edition pharmacopoeia one appendix 13), carries out percolation with 60% ethanol as solvent, collects percolation liquid, reclaims ethanol, and uses appropriate amount of water dilute, filter

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Abstract

The invention discloses the effective components of children health-care oral and relative control method, wherein the effective components comprise 0.1-0.5mg / 10ml formonitrile (HCN), more than 15mug / 10ml of hyperin content. And the preparation comprises that extracting aqua aromaticas from flower of honeysuckle, chrysanthemum, bitter apricot kernel, and capsule of weeping forsythia, heating haw thorn and 80% alcohol to extract filter liquid to be concentrated into paste to be dissolved by some water into soup, penetrating tangerine peel with 60% alcohol as solvent, collecting the penetrated liquid, recycling alcohol to be diluted via some water, combining the soups and the aqua aromaticas, adding monomer syrup, benzene carbonic acid and water to be mixed uniformly, filtering to obtain the product. The inventive drug has better treatment effect, stable and controllable quality and improved safety.

Description

technical field [0001] The present invention relates to the field of medicine, in particular to the active ingredient control of Jianer Qingjie Liquid, which has the functions of clearing away heat and detoxification, eliminating phlegm and relieving cough, eliminating stagnation and neutralizing, and is used for oral erosion, cough and sore throat, loss of appetite, abdominal fullness, etc. Methods. Background technique [0002] The Jianer Qingjieye drug involved in this invention is a national standard variety. Jianer Qingjieye is currently one of the drugs that can treat both respiratory and digestive system diseases in clinical practice. Its market share has accounted for 50% of the current children's medicine %above. Jianer Qingjieye currently has 17 domestic companies with production approval documents issued by the State Food and Drug Administration, and about 7 products are sold in the market. Due to historical reasons, these products generally have unclear active ...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P11/04A61P11/10A61P11/14A61P1/02A61P1/14G01N30/02G01N33/15
Inventor 易八贤
Owner SINOPHARM GRP ZHIJUN SHENZHEN PINGSHAN PHARMA CO LTD
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