Thipronin enteric-coated delayed-release agent

A tiopronin enteric and slow-release preparation technology, which is applied in antidote, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of large fluctuations in drug concentration and reduce direct stimulation Sexuality, good for long-term treatment, avoid nausea effect
CN101045044AInactive Publication Date: 2007-10-03้ญ็ง€ๅŽ

Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
้ญ็ง€ๅŽ
Publication Date
2007-10-03
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

A slow-releasing enteric tiopronin without stimulation and by-effect is prepared from tiopronin (3-65 Wt%), slow-releasing material (5-90) and enteric coating material (3-30).
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Description

technical field

[0001] The invention relates to an enteric-coated slow-release preparation of tiopronin, which belongs to the field of chemical drug preparations. Background technique

[0002] Tiopronin (English name: Tiopronin) is a metabolic improvement antidote, its molecular formula: C 5 h 9 NO 3 S, molecular weight: 163.20, structural formula as follows:

[0003]

[0004] Tiopronin can be used to restore liver function and adjuvant therapy in patients with chronic hepatitis. Animal experiments have shown that tiopronin has a preventive effect on acute liver injury in mice caused by carbon tetrachloride, ethanol and D-galactosamine. It can protect the structure of liver mitochondria and improve its function. This product is to TAA (thioacetamide), CCl 4 (Carbon tetrachloride) can reduce the increase of serum AST and ALT in the acute liver injury model of animals, and can inhibit the accumulation of triglycerides caused by the chronic liver injury model; it can p...

Claims

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