Thipronin enteric-coated delayed-release agent
Patent Information
- Authority / Receiving Office
- CN ยท China
- Current Assignee / Owner
- ้ญ็งๅ
- Publication Date
- 2007-10-03
- Estimated Expiration
- Not applicable ยท inactive patent
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Abstract
Description
technical field
[0001] The invention relates to an enteric-coated slow-release preparation of tiopronin, which belongs to the field of chemical drug preparations. Background technique
[0002] Tiopronin (English name: Tiopronin) is a metabolic improvement antidote, its molecular formula: C 5 h 9 NO 3 S, molecular weight: 163.20, structural formula as follows:
[0003]
[0004] Tiopronin can be used to restore liver function and adjuvant therapy in patients with chronic hepatitis. Animal experiments have shown that tiopronin has a preventive effect on acute liver injury in mice caused by carbon tetrachloride, ethanol and D-galactosamine. It can protect the structure of liver mitochondria and improve its function. This product is to TAA (thioacetamide), CCl 4 (Carbon tetrachloride) can reduce the increase of serum AST and ALT in the acute liver injury model of animals, and can inhibit the accumulation of triglycerides caused by the chronic liver injury model; it can p...