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Use of chelerythrine extracted from plant for killing snall

A technique for chelerythrine and oncomelania, which is applied to the application field of alkaloid-chelerythrine in killing oncomelania, the intermediate host of schistosomiasis, can solve the problems that have not yet been discovered, and achieves good snail killing effect, wide sources, low price effect

Inactive Publication Date: 2007-11-14
HUNAN NORMAL UNIVERSITY
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  • Abstract
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Problems solved by technology

[0009] According to literature reports, chelerythrine can treat asthma, bronchitis, dysentery and other diseases, and also has analgesic, liver-protecting, anti-tumor effects, but so far, no literature reports on its other uses have been found

Method used

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  • Use of chelerythrine extracted from plant for killing snall

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Embodiment Construction

[0022] The present invention will be further described below in conjunction with embodiment.

[0023] According to the immersion method stipulated in the WHO "Molluscicide Laboratory Final Screening Method", the laboratory chelerythrine killing oncomelania test was carried out. The chelerythrine content of the sample was 98%.

[0024] (1) Prepare chelerythrine into 8 groups of aqueous solutions with different concentrations (concentrations are 100.0mg / L, 50.0mg / L, 25.0mg / L, 12.5mg / L, 6.25mg / L, 3.125mg / L, 1.5625mg / L, 0.78125mg / L), 2000ml for each group. Set up a dechlorinated water blank control;

[0025] (2) The snails were collected from endemic areas the day before, and live snails were selected on the day of the test, and packed into special nylon bags in groups of 50;

[0026] (3) Put 1 bag of Oncomelania per 500ml of solution (i.e. 1 Oncomelania per 10ml of liquid medicine), put 4 bags of Oncomelania snails into each concentration sample solution, put it in an incubato...

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Abstract

The present invention relates to an application of chelerythrine extracted from plant for killing oncomelaniae. It is characterized by that the chelerythrine can be prepared into aqueous solution whose concentration is 1.5-100.0mg / L, said chelerythrine aqueous solution can be used for soaking oncomelaniae for 96h, its killing rate for killing oncomelaniae can be up to 44-10%.

Description

technical field [0001] The invention relates to a snail killing agent, in particular to the application of chelerythrine, an alkaloid extracted from plants, in killing snails, the intermediate host of schistosomiasis. Background technique [0002] Schistosomiasis is a zoonotic parasitic disease prevalent in 74 countries in the world. According to WHO estimates, 600 million people in the world are at risk of schistosomiasis infection, of which about 200 million people are infected. China's Yangtze River Basin and 12 provinces (municipalities, autonomous regions) south of it are endemic. There are 434 endemic counties in China, with a population threatened by infection of more than 66 million and chronic patients of 840,000. It is estimated that new infection or reinfection will occur every year. The number of people is over 200,000, and the area with snails is 384599.97h m 2 . Controlling and blocking the spread of schistosomiasis is an important countermeasure to control s...

Claims

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Application Information

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IPC IPC(8): A01N43/90A01P9/00
Inventor 彭飞刘年猛孙慧刘铭黄琼瑶
Owner HUNAN NORMAL UNIVERSITY
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