Ginkgo flavone and lactone dispersion tablet and preparation method thereof

Abstract

The invention relates to a gingko ketonic ester dispersible tablet and its preparation method, and belongs to the field of Chinese traditional medicine. The tablet mainly comprises gingko ketonic ester and proper adjuvant. The inventive preparation has effects in activating blood circulation, dispelling blood stasis, and dredging meridians. The inventive dispersible tablet has improved water solubility and can rapidly disinregrate in cold water and form uniform suspensoid liquid. It has various administration manner including direct drink, direct deglutition, sublingual administration. It has convenient administration, high bioavailability, good taste, easy acceptability, rational and feasible technology, and stable and controllable quality.

Description

technical field [0001] The invention relates to a ginkgo ketone ester dispersible tablet for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, belonging to the technical field of medicines. technical background [0002] Cardiovascular and cerebrovascular diseases are the number one killer of human health, and have the characteristics of high morbidity, high mortality, and high disability rate. . According to reports, 2.6 million people die from cardiovascular and cerebrovascular diseases in my country every year, and one person dies from such diseases every 12 seconds. Therefore, prevention and treatment of cardiovascular and cerebrovascular diseases have become a serious and arduous task before us. topic. In this battle against cerebral ischemic injury, Ginkgo biloba preparations have emerged and attracted worldwide attention. With the continuous development of medicine and chemical industry, ginkgo ketone ester, the main active ingred...

AI Technical Summary

Problems solved by technology

However, because the ginkgolides in the ginkgo esters are insoluble in water, and the aglycone components in the flavonoids are also insoluble in water, the granules made are suspended granules, and the fine powder of the ginkgo esters has a low dispersion, which affects the lactones. and the dissolution and absorption of flavonoids; at the same time, with the continuous development of preparation technology, new dosage forms that are more conducive to disease treatment continue to emerge, while the drop pills in the current formulations of ginkgo ketone esters on the market are still blank; combined with the priority of the disease, One formulation is not enough