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Composite preparation for treating epithelial erosion and preparation method thereof

A compound preparation and epithelium technology, applied in the field of medicine, can solve the problems of easy infection, side effects, and inconvenience for patients, and achieve the effects of promoting granulation tissue proliferation and treating cervical erosion.

Active Publication Date: 2008-04-23
海南森瑞谱生命科学药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, after physical therapy, the cervix is ​​narrowed or even closed, and some have symptoms such as weakness, dizziness, and even cardiac arrest; in addition, the vaginal discharge and bleeding take a long time, which is easy to cause infection and inconvenience to the patient. Also pay attention to the selection of indications and the need for skilled professionals to manipulate
However, the current drug treatment methods have no obvious effect, are prone to relapse and have side effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Obtain yellow juice (main components include anthraquinone and its glycosides, naphthone, resin, organic acid and other active substances and components) from the leaf bark of aloe and freeze-dry or spray-dry it to make aloe yellow juice dry product; Then The dried product of the aloe vera yellow juice is mixed with immunoactive substances, antibacterial / bacteriostatic agents, and bioadhesive or mucoadhesive carriers to make freeze-dried powders, lotion smears, suppositories, granules, sprays, pill emulsions, Solution, suspension or their sustained-release and controlled-release dosage forms, wherein the content (weight) of the dried product of the yellow aloe juice is 0.05-15%, and the immunoactive substance is aloe gel freeze-dried product or aloe gel spray-dried , dried product, the described bactericidal / bacteriostatic agent is one or more of chlorhexidine dextrose, chlorhexidine acetate, and neogiltamine, and the bioadhesive or mucoadhesive carrier includes hydroxyp...

Embodiment 2

[0034]Obtain yellow juice (main components include anthraquinone and its glycosides, naphthone, resin, organic acid and other active substances and components) from the leaf bark of aloe and freeze-dry or spray-dry it to make aloe yellow juice dry product; Then The dry product of the aloe yellow juice is mixed with antiviral bioactive substances, immune active substances and stable protective agents to make freeze-dried powder, lotion, capsule, smear, suppository, ointment, granule, spray, drop pill emulsion, solution , suspension or their slow-release and controlled-release dosage forms, wherein the content (weight) of the dried product of aloe vera yellow juice, antiviral bioactive substances, immune active substances and stable protective agent is 0.05-15%, 0.1-10% respectively , 70-98.9%, the immune active substance is aloe gel freeze-dried product or aloe gel spray drying, the antiviral active substance includes natural pokeweed antiviral protein or recombinant pokeweed an...

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PUM

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Abstract

The present invention relates to a compound preparation for effectively curing epithelial erosion. Said compound preparation includes 0.05-15% of aloe yellow juice dried product, immunological competent substance, bactericidal / bacteriostatic agent and biological adhesive or mucosal adhesive carrier, in which the described immunological competent substance is freeze-dried aloe gel product or aloe gel spray-dried product, the described bactericidal / bacteriostatic agent is one kind of chlorhexidine digluconate, chlorhexidine acetate and new benzalkonium chloride or several kinds of them, and the described biological adhesive or mucosal adhesive carrier includes one of hydroxypropyl methyl cellulose, carbomer, alginate, pectine, xylose polyglucosan and polycarbophil or several kinds of them. Said invention also provides its correspondent preparation method, and said compound preparation can be used for effectively curing the diseases of female genital viral and bacterial infection and cervical erosion, etc.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a compound preparation for treating epithelial erosion and a preparation method thereof. Background technique [0002] Chronic cervicitis is a persistent inflammation of the cervix, usually in women of reproductive age. In severe cases, symptoms include a thick, irritating, foul-smelling discharge with pelvic pain. The appearance of the cervix is ​​congested and enlarged, and there are symptoms of old lacerations caused by cervical ectropion and common childbirth. Cervical erosion is the most common pathological change in chronic cervicitis. It is a red area formed by cervical squamous epithelial cells replaced by columnar epithelium. It is the most common disease in gynecology. It is mostly transformed from acute cervicitis. Its treatment is not complete, or it is not treated for pathogens, which makes the disease protracted. [0003] Modern medicine has confirmed that bacterial and v...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K38/16A61K38/21A61K9/02A61K9/06A61K9/08A61K9/10A61K9/12A61K9/14A61K9/19A61K9/48A61P15/00A61P17/02A61P31/04A61P31/12A61K31/137A61K31/155A61K31/715
Inventor 易小平邓柳红杨卫帆张春发
Owner 海南森瑞谱生命科学药业股份有限公司
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