Medicinal composition for resisting bacteria and mycoplasma affection for birds and preparation thereof

Abstract

The invention relates to a medicine compound used by birds to fight against bacteric and mycoplasma infection, and the method for preparing the medicine compound. The ingredients and the weight percentages of the ingredients are respectively 5 to 15 percent ofloxacin (acid salt), 1 to 5 percent synergistic agent, and 100 percent other additive accessories. The preparation method is showed as follows: mixing the ofloxacin (acid salt), the percent synergistic agent and the additive accessories, which are crushed and screened, according to the weight percentages, and then fully agitating, so a medicine composite used by birds to fight against bacteric and mycoplasma infection comes into being. The ofloxacin (acid salt) in the invention influences the duplication, transcription, reparation and reconstitution of the DNA of the bacteria through restricting the bacteria topoisomerase IV and the DNA gyrase, thus achieving the antibiosis function. The synergistic agent can restrict the dihyrofolate reductase and impede the metabolism and utilization of the folic acid of the sensitive bacteria, both of which, under the coordination, have a function of double impeding, with the antibiosis effect being decades greater. The formulation of the invention is scientific, good in terms of antibiosis and convenient in use, only need to be directly added into the drink water, and is applicable for large-scale production.

Description

technical field [0001] The invention belongs to the field of pharmaceutical compositions, in particular to a pharmaceutical composition for poultry against bacteria and mycoplasma infection and a preparation method thereof. Background technique [0002] my country's modern poultry industry started late, but developed rapidly. With the increase and scale expansion of intensive poultry farms, bacterial diseases have increased significantly. Such as chicken colibacillosis, salmonellosis, staphylococcus disease, pseudomonas aeruginosa disease, chicken coccidiosis, chicken leukocytic protozoon disease, chicken pasteurellosis, etc. People usually take a series of comprehensive defense measures to reduce the development and prevalence of such diseases. However, due to the emergence of bacterial drug resistance, the mixed infection of various diseases, and the ineffectiveness of epidemic prevention measures, these diseases have not been eradicated, and they occur from time to time...

AI Technical Summary

Problems solved by technology

Poultry bacterial diseases and mycoplasma infections have brought huge economic losses to farmers. However, due to the abuse and abuse of drugs, many drugs have developed drug resistance, which can no longer prevent and control the increasing types of poultry diseases and Atypicalization of the disease, and mixed infections, etc.