Method for preparing decoquinate premix

Abstract

The invention discloses a preparing method of deccox, which uses cheap pyrocatechol as material to obtain deccox products with good quality and low cost by diethoxylation, nitration, alkali hydrolysis, decyloxylation, reduction, condensation, ring closing and hydrolyzation. Compared with the prior art, materials such as 3,4-dihydroxynitrobenzene or catechol ethylether, which are expensive and not easy to buy, are replaced by chemical materials, such as plate caustic soda, pyrocatechol, diethyl sulfate, glacial acetic-acid, nitric acid, glycol monoethyl ether, potassium hydroxide, bromodecane, phosphorus oxychloride, ethoxymethylene, sodium hydroxide, etc., which are cheap and easy to obtain, the reaction condition is gental, the integration cost is 50% lower than that of the prior art.

Description

Technical field: [0001] The invention relates to a preparation method of poultry medicine, in particular to a preparation method of dichnidine. Background technique: [0002] Antiballin, also known as decoquinate, can prevent and control E. tenella, E. maxima and E. acervulina , Poultry coccidiosis caused by poisonous Eimeria (E.necatrix), Eimeria brunetti (E.brunetti), variant Eimeria (E.mivati), etc. It works early in the coccidia life cycle and lasts the longest. It has a good effect on the six most harmful poultry coccidia. Play a role in the asexual reproduction stage of coccidia. After entering the sporozoite cell, it prevents its development by interfering with DNA synthesis. Dnifloxacin starts to play a role in the early life cycle of coccidia, so as to avoid damage to poultry intestines, and can more effectively help farmers obtain higher economic benefits. [0003] Product properties: [0004] Chinese name: enemy ball element, decoquinate; [0005] English n...

AI Technical Summary

Problems solved by technology

[0021] In method 1., since 3,4-dihydroxynitrobenzene is not produced domestically, the import cost is very high, and ring closure is to use diphenyl ether as a solvent at 250° C., which has large environmental pollution and lower yield (only 50% )Defects

[0022] In method ②, o-hydroxyphenetole is used as raw material. Although phenetole is produced in China, the cost is relatively high, requiring 200,000 / ton. The cost of the finished product produced by this method is relatively high, and there is no market competitiveness

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