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Herbicide composition and its preparation and application, medicament use

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and preparation thereof, can solve the problems of unsatisfactory clinical efficacy of neuroprotective agent, lack of basic and clinical research, etc., achieve obvious neuroprotective effect, improve quality of life, and promote neurological The effect of functional recovery

Inactive Publication Date: 2008-08-27
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, in actual clinical practice, nerve damage often involves a variety of pathological processes. The clinical efficacy of any of the above-mentioned neuroprotective agents is not ideal, and there is a lack of relevant basic and clinical research for combined use. Therefore, research on neuroprotective agents Like clinical use, breakthroughs in ideas or methods of use are urgently needed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] The present embodiment is the traditional Chinese medicine composition (granule) that is made by the crude drug of following weight portion proportioning:

[0062] 1 part of ginseng stem and leaf, 25 parts of Erigeron breviscapitalis.

[0063] The present embodiment Chinese medicine composition (granule) is made by the method comprising following main steps:

[0064] (1) Extracting ginseng stems and leaves: take the ginseng stems and leaves in said weight portion, add 8 times the amount of water to decoct and extract 3 times, each time for 1 hour, filter, combine the filtrates, and concentrate to a thick paste.

[0065] (2) Extracting Erigeron scutellariae: Take the Asarum scutellariae in said weight portion, add 70% ethanol to extract twice, each time for 1 hour, filter, combine the filtrates, recover ethanol, and concentrate to a thick paste.

[0066] (3), make granules: mix the thick paste of ginseng stems and leaves prepared by the above step (1) and the thick past...

Embodiment 2

[0068] Present embodiment is the traditional Chinese medicine composition (capsule) that is made by the crude drug of following weight portion proportioning:

[0069] 3 parts of ginseng, 20 parts of Erigeron breviscapitalis.

[0070] The present embodiment Chinese medicine composition (capsule) is made by the method comprising following main steps:

[0071] Take the ginseng and Erigeron breviscapus in said parts by weight, add 10 times of 60% ethanol to extract 3 times, each time for 1 hour, filter, combine the filtrate, recover ethanol, and concentrate to dryness, add the total amount of the above two extracts 30% starch, granulated, dried, filled into capsule shells, made into capsules, inspected, and obtained.

Embodiment 3

[0073] The present embodiment is the traditional Chinese medicine composition (tablet) that is made by the crude drug of following weight portion proportioning:

[0074] 5 parts of ginseng stems and leaves, 15 parts of Erigeron breviscapus.

[0075] The present embodiment Chinese medicine composition (tablet) is made by the method comprising following main steps:

[0076] (1), extract ginseng stem and leaf:

[0077] ①Water extraction: take the ginseng stems and leaves of the stated weight portion, pulverize, add water and extract 3 times, add 10 times the amount of water for 3 hours for the first time, add 8 times the amount of water for 2 hours for the second time, add 6 times the amount for the third time Double the amount of water extraction for 0.5 hours, combine the water extracts, and concentrate to 1 / 2 of the weight of the medicinal materials;

[0078] ② Alcohol precipitation: Add ethanol to the concentrated water extract of the above ① to make the ethanol concentrati...

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Abstract

The invention discloses a traditional Chinese medicine combination, which is formed by raw medicines according to the proportion by weight as follows: ginseng or ginseng cauline leaf is 1 to 15 parts, and erigeron is 5 to 30 parts. Adopting the conventional traditional Chinese medicine combination formula, the invention has obvious neuroprotective effect and neural function improving, etc., by combining with the characteristics and advantages of the Chinese herb compound that are multi-component, multi-target, multi-level and multiple ways for treating complex disease; the invention can effectively block most pathological mechanisms of a plurality of disease nerve injury such as ischemic cerebrovascular disease, etc.; more particularly, for the improved aspect to the neurological symptom, the traditional Chinese medicine injection is helpful to enhance the living quality of a patient, and achieves the purpose of improving prognosis, and has important clinical application significance. The invention further discloses a preparation method of the traditional Chinese medicine combination and the pharmaceutical application.

Description

technical field [0001] The invention belongs to the technical field of medical preparations, and in particular relates to a traditional Chinese medicine composition, a preparation method and a medical application thereof. Background technique [0002] Nerve injury mainly includes cranial nerve injury, spinal cord injury and peripheral nerve injury. [0003] Cranial nerve injury includes traumatic brain injury, sequelae of cerebrovascular sclerosis (cerebral hemorrhage, cerebral thrombosis), sequelae of encephalitis and meningitis, sequelae of demyelinating diseases and other sequelae of cerebrovascular diseases. [0004] Cerebrovascular disease is a common disease worldwide. In my country, ischemic cerebrovascular disease is the main disease. It has the characteristics of high morbidity, high fatality rate and high disability rate. Once it occurs, it will bring great harm to patients and families mental distress and financial burden. [0005] According to the results of mod...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61P25/00A61P25/02A61P9/10
Inventor 唐德江陈犁李文军
Owner 重庆希尔安药业有限公司
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