Medical composition containing derivative of vitamin B group
A composition, technology of vitamins, applied in the field of pharmacy
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Embodiment 1
[0007] Example 1 Benfotiamine+B6+B12 Tablets
[0008] prescription:
[0009]
[0010] Component Dosage
[0011]
[0012] Benfotiamine 10g
[0013] B6 10g
[0014] B12 25g
[0015] Microcrystalline Cellulose 235g
[0016] CMS-Na 10g
[0017] Micronized silica gel 2g
[0018] A total of 1000 pieces were made
[0019]
[0020] Preparation:
[0021] Pass benfotiamine, B12, and microcrystalline cellulose through 80-mesh sieve respectively, mix evenly, dissolve B6 in 50% ethanol solution and add to the mixed powder, make soft material, granulate with 24-mesh sieve, dry, 20-mesh sieve For granulation, add micropowder silica gel and CMS-Na, mix evenly, and press a suitable die to form a tablet.
[0022] If the above-mentioned tablet is coated, a coated tablet can be obtained, which can be a film-coated tablet, an enteric-coated tablet, and the like.
Embodiment 2
[0023] Example 2: Benfotiamine + pyridoxal phosphate + methylcobalamin capsules
[0024] prescription:
[0025]
[0026] Component Dosage
[0027]
[0028] Benfotiamine 10g
[0029] Pyridoxal Phosphate 10g
[0030] Methylcobalamin 0.5g
[0031] Starch 150g
[0033]
[0034] Preparation:
[0035] Pass the benfotiamine, pyridoxal phosphate, mecobalamin and starch through a 80-mesh sieve, mix them uniformly according to the method of equal volume addition, then add magnesium stearate, mix them uniformly, pack separately, and obtain the product.
[0036] The used capsule shell can be a common capsule or an enteric-coated capsule.
Embodiment 3
[0037] Example 3: Benfotiamine+B2+B6+B12 chewable tablet
[0038] prescription:
[0039]
[0040] Component Dosage
[0041]
[0042] Benfotiamine 10g
[0043] B2 5
[0044] B6 10
[0045] B12 25
[0046] Xylitol 175
[0047] Mannitol 150
[0048] Sweet orange essence 10g
[0049] Aspartame 5g
[0050] 2% PVPk-30 ethanol solution appropriate amount
[0052]
[0053] Preparation:
[0054] Pass raw and auxiliary materials such as benfotiamine, B2, B12, xylitol, and mannitol through a 80-mesh sieve, and mix them uniformly by using the method of equal increments, and dissolve B6 in 2% PVP-k30 ethanol solution to make a soft material, 16 Granulate with a mesh sieve, dry, granulate with a 20-mesh sieve, add other flavoring agents, sweeteners, and glidants, mix evenly, and compress into tablets.
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