Anti-dermatophyte compound preparation

Abstract

The invention relates to a compound preparation for resisting dermatophyte, the name of which is 'compound anti-ringworm agent', belonging to the pet clinical drug research and development field. 50g of 5 Chinese traditional medicines of scutellaria, figwort, Chuangxiong, pseudolarix and magnolia officinalis are picked up respectively and added with 1,000 to 1,500mL of water, boiled by slow fire,heated and concentrated to 250mL of compound Chinese traditional medicine stock solution, the compound Chinese traditional medicine stock solution is subject to twenty-time dilution, added with acetic acid with a concentration of 1.25mg / mL, and the compound preparation liquid for resisting dermatophyte is obtained. The pungency and safety tests of the compound anti-ringworm agent show that the compound preparation has no pungency and toxicity on skin; the medicinal effect research shows that the compound preparation can effectively inhibit surface fungi of dog; the compound anti-ringworm agent is used for the whole-body medicated bath twice a week with 30 minutes each time; a spray prepared by the compound anti-ringworm agent is used to be sprayed on affected parts twice / d with successiveapplication of 14d; and the fungus inhibiting ratio after the application of the compound anti-ringworm agent is 99.9 percent.

Description

Anti-skin fungus compound preparation 1. Technical Field The invention relates to an anti-skin fungus compound preparation, which belongs to the field of pet clinical drug research and development. 2. Background technology In veterinary clinical practice, canine dermatomycosis is a very common and frequent disease. Pathogenic fungi adhere to dog skin excessively, invade skin hair or toenails, proliferate in large quantities, and cause organic skin lesions. Canine dermatomycosis has a long course, is difficult to cure, and is easy to relapse. It can spread from animal to animal, human to human, and human to animal, causing serious public health problems. The average morbidity rate is about 10% to 40%, and the morbidity rate is high, and the recurrence rate is also high, which has attracted increasing attention from veterinary clinicians. At present, commonly used antifungal drugs mainly include polyenes, azoles, allylamines, cell wall inhibitors, etc. Although these drugs and...

AI Technical Summary

Problems solved by technology

The purpose of the present invention is to develop a compound antifungal preparation combining Chinese and Western medicines against the reality that there is still a lack of antifungal Chinese medicine compound in veterinary clinics at present.

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