Reagent kit for parting detection of HLA-DRB1 gene

A technology for HLA-DRB1 and genotyping, which is applied in the field of human leukocyte antigen gene detection and typing kits, can solve the problems of low probe hybridization specificity, improve specificity, increase detection throughput, and avoid Effect of false positive and false negative problems on probe hybridization results
CN101314790BActive Publication Date: 2010-12-29DAAN GENE CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
DAAN GENE CO LTD
Publication Date
2010-12-29

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Abstract

The invention relates to a gene detecting kit used for clinical detection, in particular to the kit which adopts a DNA micro-array chip and a dual-temperature hybridization probe to execute the detection and typing on human leukocyte antigen gene in a high-throughput, high-efficiency and high-specificity manner and the usage thereof.
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Description

Technical field

[0001] The invention relates to a gene detection kit, in particular to a kit for detecting and typing the human leukocyte antigen gene by using DNA microarray and dual-temperature hybridization technology and its preparation and use method. technical background

[0002] HLA (Human leukocyte antigen, human leukocyte antigen) is the main human histocompatibility system. Histocompatibility refers to the degree of acceptance by both the donor and the recipient when tissue or organ transplantation is performed between different individuals. The reaction caused by the incompatibility of donor and recipient tissue has been proved to be an immune response, which is induced by alloantigens on the cell surface. This antigen representing individual specificity is called transplantation antigen or histocompatibility antigen, which plays The main antigen is called the major histocompatibility system (MHS), and HLA (human leukocyte antigen) is the major histocompatibility...

Claims

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