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Integrated urethral sling

A sling and urethral technology, applied in the field of medical devices for the treatment of women's stress urinary incontinence, can solve the problems of bladder stabbing, long puncture path, and large damage, reduce trauma, shorten puncture path, and have good biocompatibility Effect

Active Publication Date: 2012-02-22
SUMMIT GD BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And rely on the 15-18cm long curved puncture needle traction, pull the sling to the abdominal wall, the puncture path is too long, the damage is greater, once the operation is not done properly, the bladder may be stabbed

Method used

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  • Integrated urethral sling
  • Integrated urethral sling
  • Integrated urethral sling

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Take fresh membrane tissue (including fat omentum, diaphragm, pericardium) and tendons of pigs or cattle, soak them in 0.1% bromogeramine solution for 30 minutes, take them out, remove impurities such as fat and muscle attached, and wash them; Put it into the degreasing device, use isoamyl isobutyrate as an organic solvent to extract the fat existing in the membrane and tendon tissue, take it out, and wash it; put it into the decellularization reactor, add pepsin and trypsin, the concentration is 120mg / liter, enzymatic hydrolysis for 4-16 hours, take it out, and wash; put it into an epoxy fixation reactor, put tert-hexane oxide at a concentration of 0.1N-1.0N, let it react for 24-96 hours, take it out, wash it Clean; put it into the antigen removal reactor, first add the nucleophilic reagent of valeryl chloride with a concentration of 1%-10%, make the reaction for 4-12 hours, neutralize the excess acid chloride, wash, and then add the nucleophile with a concentration o...

Embodiment 2

[0030] Such as image 3 As shown, the difference between this embodiment and Embodiment 1 is that this example is made of medical polypropylene material by the following method: the medical polypropylene is processed into a film or a braided mesh, and it is cut into a width of 10mm, a length of 100mm, two The sling 1 with the T-shaped tie at the end will punch holes on the band for the film band. The puncture fixing head 2 as described in Example 1 is formed by injection molding or molding, the suspension belt 1 is wrapped around the groove at the tail of the puncture fixing head 2, and it is welded and fixed by ultrasonic welding to obtain the following: image 3 Shown product, pack, sterilize, get final product.

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Abstract

The invention discloses a structure and a preparation method of a novel integrated urethral sling. The integrated urethral sling is composed of a suspension belt and puncture fixing heads fixed at both ends of the belt. The suspension belt is a porous membrane belt or braided belt with a width of 5-20mm and a length of 40-120mm. The piercing and fixing head is a bullet body with barbs, which can only be advanced and cannot be reversed. It will be fixed wherever it pierces, and it plays the role of piercing and fixing at the same time. Whether it is a sling or a puncture fixation head, it is made of animal tissue as a raw material through a series of biochemical treatments such as epoxy cross-linking, multi-directional antigen removal, mechanical modification and induced activity modification, and then specially designed processing and molding technology. High stability, good biocompatibility, no adverse reactions caused by foreign body stimulation after implantation, can quickly integrate with the patient's tissue, induce autologous fibrous tissue to grow in, and finally form a suspension fixation of the own tissue. The utility model has the advantages of convenient use, less trauma and good therapeutic effect.

Description

technical field [0001] The invention relates to a medical device for treating women's stress urinary incontinence, which belongs to implantable medical devices. Background technique [0002] Women's stress urinary incontinence is a common disease of middle-aged and elderly women, and the incidence rate is more than 30% among women over 50 years old. At present, the commonly used surgical treatment method is urethral and bladder neck suspension. A urethral sling. Most of these urethral straps are made of synthetic materials, with complicated structures and complicated operations. Some are made into a knapsack style, some are made into a long belt style, and some are fixed by surgical sutures. Some do not need to be sutured, so they have to be fixed by the side thorns of the sling. For this reason, the side thorns of the sling should be made hard and sharp, so that they can easily penetrate into the vagina or bladder. And it needs to be pulled by a curved puncture needle wi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/00A61F2/02A61L31/04
CPCA61L31/005A61L2430/40A61F2/0045A61B2017/00805
Inventor 童晓文徐斌徐国风
Owner SUMMIT GD BIOTECH
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