Double-layer traditional Chinese medicine patch for treating oral ulcer and preparation method thereof
A technology of oral ulcer and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine oral ulcer double-layer patch and its preparation. The effect of slow release, reduction of systemic side effects, and pain relief
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Embodiment 1
[0039] 1. 8 grams of Evodia rutaecarpa, 15 grams of Qingdai, 5 grams of licorice, and 10 grams of Chinese gall, decocted in water for 3 times, 2 hours each time, and concentrated the water extract to a specific gravity of 1.2-1.4, then centrifuged at a high speed; 2. Centrifuged liquid or concentrated Dried to obtain the crude extract; 3. Macroporous resin, eluted with water, concentrated after decolorization of the eluent, precipitated with 95% ethanol, placed in the refrigerator, filtered, vacuum-dried the filter cake, crushed and sieved or spray-dried to obtain off-white Extract in fine powder form.
Embodiment 2
[0041] Reflux 12 grams of Evodia rutaecarpa, 20 grams of Qingdai, 10 grams of licorice, and 15 grams of Gallnut, reflux with 75% ethanol, extract 3 times, concentrate the filtrate into an extract, add water to make the extract into a suspension, wash with macroporous resin D301 After decolorization, the eluate is concentrated, precipitated with 95% ethanol, placed in the refrigerator, filtered, and the filter cake is vacuum-dried, pulverized, sieved or spray-dried to obtain an off-white fine powder extract.
Embodiment 3
[0043] 10 grams of Evodia rutaecarpa, 150 grams of Qingdai, 8 grams of licorice, 15 grams of Chinese gall, 10 grams of Evodia, 150 grams of Qingdai, 8 grams of licorice, and 15 grams of Chinese gall, refluxed with 95% ethanol, extracted twice, concentrated the filtrate into an extract, added water Make the extract into a suspension, elute with macroporous resin D301, water, decolorize the eluent, concentrate, precipitate with 95% ethanol, place in the refrigerator, filter, vacuum dry the filter cake, crush and sieve or spray dry to obtain the White fine powder extract.
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