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Bulk production method of micro-fluidic chip

A microfluidic chip, mass production technology, applied in the direction of coating, etc., can solve the problem that microfluidic chips cannot be produced in batches, and achieve the effect of fast production speed

Active Publication Date: 2009-07-01
CHINESE ACAD OF INSPECTION & QUARANTINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The purpose of the present invention is to solve the problem that the current microfluidic chips cannot be produced in batches, and to provide a simple and fast batch production method for microfluidic chips

Method used

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  • Bulk production method of micro-fluidic chip

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Embodiment Construction

[0028] Such as figure 1 it is good figure 2 As shown, the mass production method of the microfluidic chip of the present invention uses a precision electric injection molding machine and a mold. This injection molding machine comprises: vertical feeding cylinder 7, horizontal material cylinder 8 and discharge port 9, and screw rod 11 is housed in the horizontal material cylinder 8, mold comprises: movable mold 5 and static mold 6 and mold core, and this mold core comprises: Left moving core part 1, left static core part 2, right moving core part 3 and right static core part 4. The discharge port 9 is aligned with the injection port 10 between the movable mold 5 and the static mold 6 .

[0029] The batch production method of the microfluidic chip of the present invention comprises the following steps:

[0030] (a) Choose a mold core made of cemented carbide material with a surface polishing degree of 0.02-0.06 microns. The mold core is J05 hard alloy steel with a hardness o...

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Abstract

The invention relates to a batch production method for a micro-flow control chip. The method comprises: a mould core made of a hard alloy material is selected; the temperature of a left movable mould core part, a left static mould core part, a right movable mould core part, a right static mould core part, a movable mould and a static mould is kept at a temperature of between 85 and 115 DEG C; a superpolymer material is evenly spread according to the thickness of between 1 and 5 centimeters and is dried for 6 to 8 hours at a temperature of between 70 and 75 DEG C; in a cleaning room with 10 thousand level to 100 thousand level at ambient temperature of between 20 and 25 DEG C, a material in a molten state is injected into the middle parts between the left movable mould core part and the left static mould core part and between the right movable mould core part and the right static mould core part; under the conditions at a speed of between 80 and 100 mm / s and pressure of between 40 and 60 MPa, the superpolymer material is injected; the whole injection time is between 27 and 33 seconds; the chip is taken out and is disinfected and sterilized; and finally, a left micro-flow control chip and a right micro-flow control chip are bonded. The method can manufacture the micro-flow control chip in large batch and promote application of micro-flow control chip technology and industrialized development.

Description

technical field [0001] The invention relates to a batch production method of microfluidic chips, in particular to a batch production method of precision injection molding of high polymer material microfluidic chips. Background technique [0002] Work in the fields of food safety testing, inspection and quarantine, and environmental monitoring urgently requires the development of rapid screening and testing methods that can be operated on-site. Microfluidic chip (Microfluidic chip) technology is the frontier of analytical technology developed in the 1990s. It uses micro-processing technology to fabricate micro-channel network structures and other functional units on substrates with a size of several square centimeters. The integration of laboratory functions such as preparation, sample injection, dilution, reaction, separation, and detection is integrated on a microchip, which is the so-called "Miniaturized total analysis system (μTAS)", also known as "Lab-on-a-Chip (Lab-on-a...

Claims

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Application Information

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IPC IPC(8): B29C45/00B29C45/33B29C45/03B29K25/00B29K83/00B29K67/00B29K23/00
Inventor 邹明强李勐
Owner CHINESE ACAD OF INSPECTION & QUARANTINE
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