Application of edible lactobacillus in preventing urinary calculus

Abstract

The invention relates to application of edible lactobacillus in the prevention of urinary calculi. Lactobacillus has the effect of decomposing oxalic acid, can degrade food-borne oxalic acid in an intestinal tract, and reduce the absorption capacity of the intestinal tract to the oxalic acid, so the lactobacillus has the efficacy of preventing calcium oxalate urinary calculi and also has important application in the fields of medicine, food and health care products. The invention proposes that the edible lactobacillus can effectively reduce the excretion of urinary oxalic acid through an animal experiment, and explore a practical way for preventing the recurrence of calcium oxalate calculi. Yoghurt which is taken as a main source of the edible lactobacillus synchronously has various remarkable health care functions and the characteristic of homology of medicine and food, and has the advantages of low cost, convenient eating, and high compliance compared with drug patients. At the same time, the yoghurt also has no any side effect and has better prevention use potential.

Description

technical field [0001] The invention relates to a method for preventing urinary calculus, specifically, the application of edible lactic acid bacteria in preventing urinary calculus. Background technique [0002] Urolithiasis is a global disease and one of the most common urological diseases, and its high recurrence rate has always troubled patients and doctors. Urolithiasis mostly calcium oxalate stones accounted for 70% to 80%. In the formation of calcium oxalate stones, the role of oxalic acid is much greater than that of calcium, and the absorption of oxalic acid in the intestine is an important factor affecting the change of urinary oxalate excretion. If a simple method can be found to effectively reduce the absorption of oxalic acid in the intestinal tract, the prevention of calcium oxalate stones will become possible. [0003] In recent years, studies have found that some lactic acid bacteria have the ability to degrade oxalic acid. Weese et al. isolated 37 strains...

AI Technical Summary

Problems solved by technology

If the preventive method cannot be done once and for all, it must be easy for patients to use it for a long time. Otherwise, no matter how good the effect is, it is only short-term and cannot achieve the purpose of long-term prevention.

Although the preventive effect of taking live bacterial preparations is good, patients need to deliberately insist on taking them, so the compliance rate is not high

Although many dairy products contain lactic acid bacteria, the amount of bacteria is usually 10 4 ~10 6 CFU / g, it is still difficult to achieve a satisfactory effect

[0005] CN1444469 discloses the use of exogenous lactic acid bacteria strains for preventing diseases related to Actinomyces naesli, wherein the lactic acid bacteria strains have the ability to adhere to the tooth pellicle and produce growth inhibitory factors; the disclosed strains of CN1264422 have immunity Strengthening effect; CN1350460 discloses a new microorganism of Lactobacillus family, especially the microorganism of the genus Lactobacillus, which can be used to prevent or treat diarrhea; and the application of edible lactic acid bacteria in the prevention of urinary calculus has not been reported

Images