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Chinese herbal medicine immunopotentiator composite for young fish of catostomid fish and preparation method thereof

A technology of immune enhancer and Chinese herbal medicine, which is applied in the direction of drug combination, medical formula, medical preparations containing active ingredients, etc. It can solve the problems of pathogen-specific limitation, drug resistance of farmed animals, and limited practical application, and achieve low equipment requirements. , enhance non-specific immunity, the effect of reasonable technology

Inactive Publication Date: 2012-07-25
HUAZHONG AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The current treatment methods for fish diseases, the traditional treatment methods represented by the use of antibiotics, are gradually banned and replaced in various countries because of their disadvantages such as easy to cause drug resistance in farmed animals and pollute the environment; although the vaccination method is effective to a certain extent , but this method is time-consuming and laborious, and has the limitation of pathogen specificity, and its practical application is very limited

Method used

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  • Chinese herbal medicine immunopotentiator composite for young fish of catostomid fish and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0025] The proportioning of propolis and Epimedium in the present embodiment is described with reference to "Summary of the Invention". 55-75% of the basic formula. The specific steps are:

[0026] Prepare as follows:

[0027] A: Grind the solid raw materials propolis and epimedium into powder respectively (use a common grinder or colloid mill, and do not particularly require the fineness of the pulverized object), and set aside;

[0028] B: soak 2 hours with 60% ethanol and commercial propolis (produced in Shennongjia forest area, Hubei Province) at a solid-to-liquid ratio (weight / volume) of 1:4, and extract twice at 60°C. The leaching time is 2 hours each time, the two filtrates are combined, filtered with suction, concentrated under reduced pressure to the extract, and dried at 60°C to obtain propolis extract with a moisture content of about 5%;

[0029] C: After soaking 2h with 60% ethanol and commercially available Epimedium (purchased from Wuhan Baicaotang Pharmacy, W...

Embodiment 2

[0032] The proportioning of propolis and Epimedium in the present embodiment is described with reference to "Summary of the Invention". 55-75% of the basic formula. The specific steps are:

[0033] A: Grind the solid raw materials propolis and epimedium into powder respectively (use a common grinder or colloid mill, and do not particularly require the fineness of the pulverized object), and set aside;

[0034] B: Soak 80% ethanol and commercially available propolis (produced in Shennongjia forest area, Hubei Province) for 4 hours at a solid-to-liquid ratio (weight / volume) of 1:2, and extract twice at 80°C. The extraction time is 1 hour each time, the two filtrates are combined, suction filtered, concentrated under reduced pressure to the extract, and dried at 50°C to obtain propolis extract with a moisture content of about 5%;

[0035] C: soak 4h with 80% ethanol and commercially available Epimedium (purchased from Wuhan Baicaotang Pharmacy, Wuhan City, Hubei Province) at a ...

Embodiment 3

[0038] The proportioning of propolis and Epimedium in the present embodiment is described with reference to "Summary of the Invention". 55-75% of the basic formula. The specific steps are:

[0039] A: Grind the solid raw materials propolis and epimedium into powder respectively (use a common grinder or colloid mill, and do not particularly require the fineness of the pulverized object), and set aside;

[0040] B: soak 1 hour with 50% ethanol and commercially purchased propolis (produced in Shennongjia forest area, Hubei Province) at a solid-to-liquid ratio (weight / volume) of 1:6, and extract twice at 60°C. The extraction time is 4 hours each time, the two filtrates are combined, filtered with suction, concentrated under reduced pressure to the extract, and dried at 80°C to obtain propolis extract with a moisture content of about 5%;

[0041] C: soak 1 hour with 50% ethanol and commercially available Epimedium (Wuhan Baicaotang Pharmacy) at a solid-to-liquid ratio (weight / vol...

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Abstract

The invention discloses a composition of Chinese herbal medicine immunopotentiators for Myxoeyprinus asiaticas juvenile and a preparation method thereof, which belong to the technical field of feed additives of aquaculture industry and preparation thereof. The composition of the immunopotentiators comprises the following compositions in percentage by weight: 25 to 45 percent of propolis extract and 55 to 75 percent of epimedium extract. The method for preparing the composition of the immunopotentiators comprises the following steps that: raw materials, namely propolis and epimedium are crushed respectively, an ethanol extraction method is used to prepare the propolis extract and the epimedium extract respectively, then the propolis extract and the epimedium extract are mixed evenly, and the mixture is dried to obtain a finished product. The composition of the immunopotentiators has the advantages that the composition obviously strengthens the non-specific immunity of the Myxoeyprinus asiaticas juvenile when added into feed according to the proportion of between 0.1 and 1 percent, and the survival rate of the breeding of the Myxoeyprinus asiaticas juvenile is improved by between 11and 15 percent.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical compositions for aquaculture, and in particular relates to a Chinese herbal medicine immunopotentiator composition for mullet juveniles and a preparation method thereof. Background technique [0002] The current aquaculture disease problem is a major bottleneck restricting the healthy development of aquaculture industry. The mullet is a rare species, and the diseases in the breeding process will cause serious economic losses, especially juvenile mullets, which often have large-scale outbreaks of epidemics. The current treatment methods for fish diseases, the traditional treatment methods represented by the use of antibiotics, are gradually banned and replaced in various countries because of their shortcomings such as easy to cause drug resistance in farmed animals and pollute the environment; although the vaccination method is effective to a certain extent , but this method is time-consumi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/296A61P37/04A61K35/64A61K35/644
Inventor 龚世园张国斌袁勇超余登航
Owner HUAZHONG AGRI UNIV