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Sterilized heterogeneous medical biomembrane and preparing method thereof

A biofilm and heterogeneous technology, applied in the direction of irradiation, skin transplantation, etc., can solve the problems of unfavorable drainage, incomplete sterilization, and sterilant residue, etc., to achieve increased permeability, better clinical effect, and thicker skin Appropriate effect

Inactive Publication Date: 2012-03-21
刘邑卿
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Both the heterogeneous sheep fetal biofilm and the heterogeneous biofilm do not contain collagen tissue of epidermal cells, or the content is very small, and the air permeability is different, which is not conducive to drainage; the use of ethylene oxide for sterilization not only cannot keep fresh, but also the sterilization is not thorough, and the product There are sterilant residues, and patients are susceptible to infection in clinical practice

Method used

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  • Sterilized heterogeneous medical biomembrane and preparing method thereof
  • Sterilized heterogeneous medical biomembrane and preparing method thereof
  • Sterilized heterogeneous medical biomembrane and preparing method thereof

Examples

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Embodiment Construction

[0023] Choose high-quality white-haired piglets of 1-3 months for epidemic prevention and quarantine. After slaughtering, take the whole back skin immediately, and spread the fur evenly on the sterilized operating table. Use a scraper to remove fat and impurities, and then immerse the whole fur in formalin disinfectant to remove the initial bacteria for the first time. After 10 minutes, wash with clean water 3 times, spread it on the operating table, and scrape off the long and short hairs of the epidermis with a scraper at an angle of 60°. According to less than the drum type M-350mm peeling machine, the length and width of the machine cutter frame are cut into rectangles, and the skins are prepared. ) for 20 minutes to remove slick oil, then rinse with running water for 5 minutes and dry, so that the water content of the skin is about 25%, cut according to the dial gauge of the skin thickness of 0.5-1.0mm, and prevent the blade from damaging the collagen layer during operatio...

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Abstract

The present invention belongs to the field of medical accessory bioengineering. The sterilized heterogeneous medical biomembrane is sterilized piglet skin and has a thickness of 0.5-1.0mm. The invention is characterized in that a plurality of gaps are distributed on the surface. Compared with the prior art, the sterilized heterogeneous medical biomembrane of the invention has a beneficial effect that the piglet skin which is a heterogeneous skin with optimal biocompatibility to the human body is selected. Appropriate thickness and the designing of gaps cause that the rewarming is quick and theusing is convenient in application. The same sterilization effect can be obtained when an electron accelerator of nuclear reactor is adopted for irradiating with a time shorter than that of the irradiation time of Cobalt-60. Furthermore no katogene exists for the dermal cells and fibrous tissue of biomembrane.

Description

technical field [0001] The invention belongs to the field of bioengineering of medical auxiliary materials, in particular to the field of replacing allogeneic human skin with heterogeneous animal skin. Background technique [0002] The use of allograft skin as a biological auxiliary material has a history of several decades in the treatment of large area burn wounds. However, there are disadvantages such as rejection, poor adhesion and low biocompatibility in the treatment. And the market is expensive. And there are international human rights disputes. Also need to change dressing (together with the allogeneic skin) several times during use in addition, cut scab, do skin grafting operation again. This will not only increase the pain of the patient, but also leave scars or pigmentation in the patient's own skin donor site, and also bring a heavy economic burden to the patient. [0003] Xenogeneic or heterogeneous biofilms have been used in the field of surgical medicine s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/10A61L2/08
Inventor 刘庚诰
Owner 刘邑卿