Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Pharmaceutical composition of curing endometriosis uterina

A technology of endometrium and composition, applied in the field of active ingredient composition of traditional Chinese medicine, can solve problems such as unsatisfactory curative effect, many side effects, and unclear pathogenesis of endometriosis

Inactive Publication Date: 2009-11-11
SOUTHWEST UNIVERSITY
View PDF0 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the etiology and pathogenesis of endometriosis are still unclear, there has been no mature plan and ideal treatment drugs. Most of them use compound oral contraceptives, progesterone, gestrinone and other drugs for treatment, with many side effects and no satisfaction. curative effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1 (1000 preparation units)

[0013] Ligustrazine 50g

[0014] Ferulic acid 100g

[0015] Corydalin 30g

[0016] Preparation method: the above three components are added to common pharmaceutical excipients, and prepared into injections, suppositories, aerosols, and transdermal preparations according to conventional methods.

Embodiment 2

[0017] Embodiment 2 (1000 preparation units)

[0018] Ligustrazine 500g

[0019] Ferulic acid 1000g

[0020] Tetrahydropalmatine 300g

[0021] Preparation method: The above three components are added with commonly used excipients in pharmacy, and prepared into pills, tablets, enteric-coated tablets, sustained-release tablets, controlled-release tablets, hard capsules, soft capsules, granules, drop pills, and micropills according to conventional methods.

Embodiment 3

[0022] Embodiment 3 (1000 preparation units)

[0023] Ligustrazine 2000g

[0024] Ferulic acid 4000g

[0025] Tetrahydropalmatine 1200g

[0026] Preparation method: the above three components are added to common pharmaceutical excipients, and prepared into oral solutions, oral suspensions, oral emulsions, syrups, etc. according to conventional methods.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine composition of curing endometriosis uterine, which is characterized by comprising 50 to 2000mg of ligustrazine (or ligustrazine phosphate and Chuangxiongzine Hydrochlorid), 100 to 4000mg of ferulic acid (or sodium ferulate) as well as 30 to 1200mg of tetrahydropalmatine (or tetrahydropalmatine sulfate). The pharmaceutical composition also comprises pharmaceutically acceptable adjuvant which is prepared into any medicament form suitable to be used in clinic. The invention aims at the pathology of the endometriosis uterine and adopts the active components of Chinese herbs such as ligustrazine, ferulic acid and tetrahydropalmatine with reliable pathology effects to provide a novel pharmaceutical composition which can resist the vein hyperplasia of ectopic endometrium, reduce the level of estrogen, raise the level of progestational hormone, resist inflammatory, kill pain and adjust immunity, thereby realizing the treatment to the endometriosis uterine.

Description

technical field [0001] The invention relates to a traditional Chinese medicine active ingredient composition for treating endometriosis, which is characterized in that the pharmaceutical composition contains the following active ingredients: ligustrazine (or ligustrazine phosphate, ligustrazine hydrochloride), ferulic acid ( or sodium ferulate), the pharmaceutical composition of tetrahydropalmatine (or tetrahydropalmatine sulfate). Background technique [0002] Endometriosis is a common disease in women of childbearing age, which mainly causes infertility, dysmenorrhea, chronic pelvic pain and other symptoms, seriously affects women's health and quality of life, and is closely related to malignant tumors. One of the difficult diseases. Since the etiology and pathogenesis of endometriosis are still unclear, there has been no mature plan and ideal drug for treatment. Most of them are treated with compound oral contraceptives, progesterone, gestrinone and other drugs, which ha...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/4965A61K31/4375A61K31/192A61P15/00
Inventor 徐晓玉陈怡张继芬冯彬彬李傲李卓恒董伟叶兰杨洋王小翠
Owner SOUTHWEST UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com